4423-07-8Relevant articles and documents
Synthesis of nitrogen heterocycles by the ring opening of pyridinium salts
Kearney, Aaron M.,Vanderwal, Christopher D.
, p. 7803 - 7806 (2007/10/03)
(Chemical Equation Presented) The century-old ring-opening reaction of pyridinium salts with tethered nucleophiles has been harnessed for a synthesis of substituted indoles and related nitrogen heterocyles. Extension of this method could lead to oxygen- and sulfur-containing heterocycles and carbocycles, as well as to applications in natural product synthesis and medicinal chemistry.