450407-04-2

Basic information

• Product Name: Boc-Tyr(t-Bu)-Pro-Phe-Pro-Gly-OMe
• Synonyms: Boc-Tyr(t-Bu)-Pro-Phe-Pro-Gly-OMe
• CAS NO: 450407-04-2
• Molecular Weight: 749.905
• Mol File: 450407-04-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Boc-Tyr(t-Bu)-Pro-Phe-Pro-Gly-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Tyr(t-Bu)-Pro-Phe-Pro-Gly-OMe(450407-04-2)
• EPA Substance Registry System: Boc-Tyr(t-Bu)-Pro-Phe-Pro-Gly-OMe(450407-04-2)

Safety Data

• Hazardous Substances Data: 450407-04-2(Hazardous Substances Data)

Upstream product

• 47375-34-8 Boc-Tyr(t-Bu)-OH 
• 77434-42-5 H-Pro-Phe-Pro-Gly-OMe 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 77434-41-4 H-Phe-Pro-Gly-OMe 
• 100008-18-2 N^α-Boc-L-Prolyl-L-phenylalanyl-L-prolyl-glycine methyl ester 
• 100008-17-1 N^α-Boc-L-phenylalanyl-L-prolyl-glycine methyl ester 
• 34290-72-7 tert-butyloxycarbonyl-prolyl-glycine methyl ester 
• 33256-35-8 H-Pro-Gly-OMe 

Downstream Products

• 72122-63-5 bovine β-casomorphin-5 
• 77451-91-3 H-Tyr-Pro-Phe-Pro-Gly-OMe 

Relevant articles and documents

A rapid and efficient synthesis of β-casomorphin employing Boc-amino acids and 9-fluorenylmethyl chloroformate as a coupling agent

The synthesis of β-casomorphin H-Tyr-Pro-Phe-Pro-Gly-OH employing Boc group for Nα-protection and 9-fluorenylmethyl chloroformate (Fmoc-Cl) for the formation of peptide bond is described. The protocol employing Fmoc-Cl as coupling reagent is found to be simple, efficient and rapid. All the intermediate peptides as well as the final protected peptide Boc-Tyr( iBu)-Pro-Phe-Pro-Gly-OMe have been isolated and fully characterized. They have been obtained in good yield and with high purity.