4834-59-7

Basic information

• Product Name: [(2-chloroprop-2-en-1-yl)sulfanyl]benzene
• CAS NO: 4834-59-7
• Molecular Formula: C₉H₉ClS
• Molecular Weight: 184.6858
• Mol File: 4834-59-7.mol

Chemical Properties

• Boiling Point: 240.3°C at 760 mmHg
• Flash Point: 99.2°C
• Density: 1.15g/cm³
• Vapor Pressure: 0.059mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: [(2-chloroprop-2-en-1-yl)sulfanyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-chloroprop-2-en-1-yl)sulfanyl]benzene(4834-59-7)
• EPA Substance Registry System: [(2-chloroprop-2-en-1-yl)sulfanyl]benzene(4834-59-7)

Safety Data

• Hazardous Substances Data: 4834-59-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
[(2-chloroprop-2-en-1-yl)sulfanyl]benzene is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a range of medicinal compounds with potential therapeutic applications.
Used in Fragrance Industry:
In the fragrance industry, [(2-chloroprop-2-en-1-yl)sulfanyl]benzene is used as a building block for the development of new and complex scent molecules. Its pungent odor can be modified and combined with other compounds to create unique fragrances.
Used in Chemical Products Manufacturing:
[(2-chloroprop-2-en-1-yl)sulfanyl]benzene is also employed in the manufacturing of other chemical products, where its versatile structure can be utilized to produce a variety of compounds for different applications.
Safety Precautions:

Upstream product

• 39557-31-8 3-iodo-2-chloropropene 
• 108-98-5 thiophenol 
• 78-88-6 2,3-Dichloroprop-1-ene 
• 882-33-7 diphenyldisulfane 
• 5651-88-7 phenyl propargyl sulfide 

Downstream Products

• 3480-90-8 1-(2-chloroprop-2-ene-1-sulfonyl)benzene 
• 76362-38-4 2-bromo-1-phenylthiomethylethan-1-one 
• 6212-77-7 1-phenylthio-1-propyne 
• 120915-19-7 (Z)-1,2-bis(phenylsulfanyl)prop-1-ene 
• 5000-44-2 1-phenylsulfonyl-2-propanone 
• 2525-44-2 trans-2--1--prop-1-en 
• 2525-54-4 3-(phenylsulfonyl)-2-(phenylthio)-1-propene 
• 2525-55-5 (prop-2-ene-1,2-diyldisulfonyl)dibenzene 
• 2525-46-4 2-Methoxy-3--prop-1-en 
• 15515-75-0 1,2,3-tris(phenylsulfonyl)propane 

Relevant articles and documents

Synthesis and structural analysis of 1,1,2-trichloro-2-[2-chloro-2-(organylsulfanyl)ethenyl]cyclopropanes: NMR, X-ray diffraction and QTAIM approach

A range of novel 1,1,2-trichloro-2-[2-chloro-2-(organylsulfanyl)ethenyl]cyclopropanes 2a-f were synthesized by reaction of (2-chloroprop-1-en-3-yl)sulfides with dichlorocarbene generated from CHCl3. The process apparently proceeds via carbenylation of sulfur atom followed by 2,3-sigmatropic rearrangement with subsequent dehydrochloration and cyclopropanation of the terminal double bond. The resulted trichlorocyclopropane derivatives were studied by 1H and 13C NMR spectroscopy as well as X-ray single-crystal analysis that revealed intramolecular CH-π interaction and the formation of intermolecular halogen bonds.

Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl

A regioselective anti-hydrochlorination of unactivated alkynes is reported. The reaction utilizes in situ generated HCl as the source of both the Cl- and H+ and is catalyzed by palladium(II) acetate, with loadings as low as 25 ppm. Removable picolinamide and 8-aminoquinoline bidentate directing groups are used to control the regioselectivity of the chloropalladation step and stabilize the resulting alkenylpalladium(II) intermediate for subsequent protodepalladation. This method provides access to a broad array of substituted alkenyl chlorides in excellent yields and with high regioselectivity. The products from this transformation were successfully derivatized via Stille coupling to a variety of trisubstituted alkene products. Reaction progress kinetic analysis was performed, shedding light on a possible mechanism for this catalytic process.

Domino reaction of 2,3-dichloroprop-1-ene with diphenyl disulfide in the system hydrazine hydrate-potassium hydroxide

2,3-Dichloroprop-1-ene reacted with diphenyl disulfide in the system hydrazine hydrate-potassium hydroxide at 30-35 C to give three products: 2-chloro-3-phenylsulfanylprop-1-ene, 1-phenylsulfanylpropadiene, and 1-phenylsulfanylprop-1-yne. Variation of tem

Highly chemoselective synthesis of aryl allylic sulfoxides through calcium hypobromite oxidation of aryl allylic sulfides

A highly chemoselective oxidation of widely substituted aryl allylic sulfides, prepared by allylation of arylthioethers with KF-Celite, to the corresponding aryl allylic sulfoxide was achieved by employing calcium hypobromite. Neither over-oxidation to sulfones nor halogenation of the aromatic rings was observed. The protocol may be successfully applied for the oxidation of substituted allylic systems (i.e., 2-haloallyl) that per se could interact with the oxidizing agent.