495415-34-4

Basic information

• Product Name: N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid
• Synonyms: N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid;1-(tert-Butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid
• CAS NO: 495415-34-4
• Molecular Formula: C₁₂H₁₈N₂O₄
• Molecular Weight: 254.28232
• Mol File: 495415-34-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid(495415-34-4)
• EPA Substance Registry System: N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid(495415-34-4)

Safety Data

• Hazardous Substances Data: 495415-34-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to protect amines and provide additional functional groups.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid is utilized as a building block for the development of new drugs, thanks to its versatility and the potential for creating a wide range of molecular structures with therapeutic properties.
Used in Organic Synthesis:
N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid is employed as a protecting group in organic synthesis to shield amines from unwanted reactions, allowing for cleaner reactions and the formation of more complex molecules.
Used in Drug Development:
In the drug development industry, N-Boc-4-cyanopiperidine-4-carboxylic acid/1-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid is used as a precursor in the creation of new drug candidates, leveraging its protective and functional properties to enhance the pharmacological profiles of potential therapeutic agents.

Upstream product

• 1016258-66-4 1-(tert-butyl) 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate 
• 362703-34-2 1-tert-butyl 4-methyl 4-cyanopiperidine-1,4-dicarboxylate 

Downstream Products

• 956460-81-4 4-(4-chloro-phenylcarbamoyl)-4-cyano-piperidine-1-carboxylic acid tert-butyl ester 
• 1035346-08-7 tert-butyl 4-((1H-indol-2-yl)methylcarbamoyl)-4-cyanopiperidine-1-carboxylate 
• 956460-83-6 4-cyano-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid (4-chloro-phenyl)amide 
• 956460-82-5 4-cyano-piperidine-4-carboxylic acid (4-chloro-phenyl)amide 
• 1143536-01-9 (R)-tert-butyl 4-(1-(4-chlorophenyl)ethylcarbamoyl)-4-cyanopiperidine-1-carboxylate 

Relevant articles and documents

COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS

Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.

PYRROLO [2,3-D] PYRIMIDIN DERIVATIVES AS PROTEIN KINASE B INHIBITORS

The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I)

UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES

This invention relates to a pharmaceutical comprising, as an active ingredient, a ureide derivative represented by formula: or a pharmaceutically acceptable salt thereof. The ureide derivative or a pharmaceutically acceptable salt thereof according to the present invention is useful for relieving pain and treating or preventing neuropathic pain.

SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY

The invention provides compounds of the formula (I) having PKA and PKB kinase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP1: HET 2a a Q G (HNCO)f 7 (R )x N * (GP1) (2) GP is a group GP2: 10 (R )r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heterocyclic group containing up to 4 heteroatom ring members; the ring V is a monocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims