Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Ethyl 2,2-diethoxyethylcyanoacetate, also known as Ethyl 2-Cyano-4,4-diethoxybutyrate (CAS# 52133-67-2), is a colorless liquid compound that is useful in organic synthesis. It is characterized by its unique chemical structure, which makes it a valuable component in the creation of various chemical products.

52133-67-2

Post Buying Request

52133-67-2 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

52133-67-2 Usage

Uses

Used in Organic Synthesis:
Ethyl 2,2-diethoxyethylcyanoacetate is used as an intermediate in the synthesis of various organic compounds. Its unique structure allows it to be a versatile building block for the development of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl 2,2-diethoxyethylcyanoacetate is used as a key component in the development of new drugs. Its chemical properties make it suitable for the synthesis of active pharmaceutical ingredients (APIs) that can be used to treat various medical conditions.
Used in Chemical Research:
Ethyl 2,2-diethoxyethylcyanoacetate is also used in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methods. This helps researchers to better understand the behavior of similar compounds and to design more efficient and environmentally friendly synthetic processes.
Used in Agrochemical Industry:
In the agrochemical industry, Ethyl 2,2-diethoxyethylcyanoacetate can be used as a starting material for the synthesis of various agrochemicals, such as pesticides and herbicides. Its unique properties make it a valuable component in the development of new products that can help to increase crop yields and protect plants from pests and diseases.
Used in Material Science:
Ethyl 2,2-diethoxyethylcyanoacetate can also be used in the development of new materials with specific properties, such as polymers with tailored characteristics for use in various applications, including coatings, adhesives, and plastics. Its versatility in organic synthesis allows for the creation of materials with improved performance and functionality.

Check Digit Verification of cas no

The CAS Registry Mumber 52133-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,3 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52133-67:
(7*5)+(6*2)+(5*1)+(4*3)+(3*3)+(2*6)+(1*7)=92
92 % 10 = 2
So 52133-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO4/c1-4-14-10(15-5-2)7-9(8-12)11(13)16-6-3/h9-10H,4-7H2,1-3H3

52133-67-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 2-cyano-4,4-diethoxybutyrate

1.2 Other means of identification

Product number -
Other names Ethyl 2,2-Diethoxyethylcyanoacetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52133-67-2 SDS

52133-67-2Relevant articles and documents

PROCESS AND INTERMEDIATES FOR PREPARING A JAK INHIBITOR

-

, (2022/03/04)

The present invention is related to processes for preparing ruxolitinib, or a salt thereof, and related synthetic intermediates related thereto.

PROCESS AND INTERMEDIATES FOR PREPARING A JAK1 INHIBITOR

-

, (2022/03/02)

The present invention is related to processes for preparing itacitinib, or a salt thereof, and related synthetic intermediates related thereto.

Synthesis and biological evaluation of some new tricyclic pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidine derivatives as potential antitubercular agents

Patil, Yogesh,Shingare, Ramesh,Choudhari, Amit,Borkute, Rachana,Sarkar, Dhiman,Madje, Balaji R.

, (2018/08/07)

A series of new tricyclic pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidines 8a–l were synthesized and characterized by IR, NMR (1H and 13C), and mass spectral analysis. The newly synthesized compounds 8a–l were inspected for their in vitro antitubercular activity against Mycobacterium tuberculosis (MTB) H37Ra using an established XTT reduction menadione assay (XRMA). The title compounds exhibited minimum inhibitory concentrations (MIC90) ranging from 0.09 to >30 μg/mL. Five compounds (8c, 8i–l) were further confirmed for their dose-dependent effect against MTB. These compounds were evaluated in the THP-1 infection model, where 8i (MIC90 = 0.35 μg/mL), 8j (MIC90 = 1.17 μg/mL), 8k (MIC90 = 2.38 μg/mL), and 8l (MIC90 = 1.17 μg/mL) demonstrated significant antitubercular activity. All the ex vivo active compounds showed insignificant cytotoxicity against the human cancer cell lines, HeLa, MCF-7, and THP-1. Inactivity of all these compounds against Gram positive and Gram negative bacteria indicates their specificity. Molecular docking studies in the active site of the sterol 14alpha-demethylase (CYP51) enzyme revealed a similar binding mode to the native ligand in the crystal structure, thereby helping to understand the ligand–protein interactions and to establish a structural basis for inhibition of MTB. The results suggest novel pharmacophores as selective and specific inhibitors against MTB that can be explored further to synthesize lead compounds against tuberculosis. In summary, the results clearly indicate the identification of some novel, selective, and specific inhibitors against MTB that can be explored further for potential antitubercular drugs.

Synthetic method of 4-chloropyrrolopyrimidine

-

Paragraph 0008; 0017, (2018/12/05)

The invention relates to a synthetic method of 4-chloropyrrolopyrimidine. The synthetic method takes ethyl cyanoacetate, bromoacetaldehyde diethyl acetal, thiourea, sodium ethoxide and hydrogen peroxide as raw materials and takes DMF, ethanol, water and phosphorous oxychloride as solvents to obtain the target product 4-chloropyrrolopyrimidine through four steps of reactions. The method improves amethod of removing a mercapto group in a third step. The mercapto group is first oxidized to sulfinic acid by using the hydrogen peroxide and then is removed under acidic conditions. The method is mild in reaction conditions, safe in operation and high in yield, is environmentally friendly, and is suitable for industrial production.

The therapeutic compound, use and related method (by machine translation)

-

Paragraph 1270; 1271, (2017/06/29)

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a compound or its salt which prevents or treats a central nervous system disease in which integration dysfunction syndrome and agnosia are enumerated as exemplary disorders.SOLUTION: The pharmaceutical composition includes the compound or its salt represented by chemical formula (A) which modulates striatal-enriched protein tyrosine phosphatase (STEP).

One-Pot Synthesis of 3-Substituted 2-Arylpyrrole in Aqueous Media via Addition-Annulation of Arylboronic Acid and Substituted Aliphatic Nitriles

Yousuf, Md,Adhikari, Susanta

supporting information, p. 2214 - 2217 (2017/05/12)

Pd(II)-catalyzed C-C coupling reactions between substituted aliphatic nitriles and arylboronic acids followed by in situ cyclodehydration have been employed for the first time to synthesize a wide variety of 3-substituted 2-aryl-1H-pyrroles in aqueous acetic acid. This one-pot synthesis is green, and it conforms to atom economy. The structures of two representative pyrroles, 3k and 5f, were confirmed by X-ray crystallographic analysis.

6-methyl 7-position-denitrified purine nucleoside compounds and application thereof

-

Paragraph 0091; 0093; 0094; 0095, (2017/09/02)

The invention discloses6-methyl 7-position-denitrified purine nucleoside compounds and an application thereof and belongs to the field of medicinal chemistry. The 6-methyl 7-position-denitrified purine nucleoside compounds or pharmaceutically acceptable salts of the compounds having characteristics of a structure shown as formula I are a kind of novel-structured compounds designed and synthesized according to protein structure characteristics of RNA virus polymerase, and the compounds can inhibit RNA viruses, thereby being capable of serving as potential drugs for preventing and treating infection of RNA viruses such as HCV (hepatitis c virus), influenza virus, HRV (rhinovirus), RSV, Ebola virus, DENV (Dengue virus), enterovirus and the like.

Alkylation of methylene-active compounds with halo acetals and hydrolysis of the alkylation products

Ismailov,Yusubov,Sadykhova,Gasymov,Ibragimova,Mamedov

, p. 1390 - 1393 (2016/11/29)

A preparative procedure has been proposed for the alkylation of CH acids with halo acetals and hydrolysis of the alkylation products to furan derivatives and lactones.

PYRIMIDINE COMPOUNDS AND PYRIMIDO INDOLE COMPOUNDS AND METHODS OF USE

-

Page/Page column 50, (2016/03/19)

The present invention discloses substituted pyrimidine and pyrimido indole compounds and optionally pharmaceutically acceptable salts, hydrates or solvates thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt, hydrate, or solvate thereof.

THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE

-

Paragraph 1563, (2015/11/16)

Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 52133-67-2