52222-81-8Relevant articles and documents
New developments in the synthesis of (e)-8-styrylflavones
De Azevedo, Orlando D. C. C.,Seixas, Raquel S. G. R.,Silva, Artur M. S.
, p. 1379 - 1384 (2015)
A novel route for the synthesis of new (E)-8-styrylflavones is reported. This methodology involves the regio- and stereoselective Heck cross-coupling reaction of 8-iodoflavones and styrene derivatives. The Heck precursors, 8-iodoflavones, were obtained through an efficient regioselective one-pot oxidative cyclization-iodination reaction of (E)-2′-hydroxychalcones by applying the iodine/dimethyl sulfoxide system.
Oxidative dimerisation of isoflavones: Synthesis of kudzuisoflavone a and related compounds
Deodhar, Mandar,Wood, Kasey,Black, David Stclair,Kumar, Naresh
, p. 1377 - 1383,7 (2020/09/02)
Kudzuisoflavone-A was successfully synthesised via oxidative dimerisation of daidzein in the presence of cuprous chloride. Appropriately substituted isoflavones also undergo regioselective oxidative dimerisation when treated with thallium trifluoroacetate to give novel 6′,6′″-biisoflavones in good yield. A rationale for the regioselectivity is proposed.