53189-78-9Relevant articles and documents
Trimethylsilylamines III: mise en evidence du compose d'addition sur les aldehydes; preparation d'aminals et de β-dialkylamino β-arylesters en milieu aprotique
Aube, Philippe,Christot, Isabelle,Combret, Jean-Claude,Klein, Jean-Louis
, p. 1009 - 1014 (2007/10/02)
Dialkylaminotrimethylsilanes react with aromatic aldehydes using trimethylsilyltriflate and tetrabutylammonium fluoride as catalysts and lead quantitatively to the corresponding aminals in aprotic media.The intermediate silylated hemiaminal can be characterized in many cases, mainly with pyridinecarbaldehydes.Aminals are obtained from aliphatic aldehydes using fluoride ion as catalyst.A one-pot synthesis of some β-dialkylamino β-arylesters from these reagents is described.