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2-Phenylglycinonitrile hydrochloride, with the chemical formula C8H7NO-HCl, is a white to off-white crystalline powder that exhibits solubility in water and alcohol. It is a versatile chemical compound used as an intermediate in the synthesis of various products, including pharmaceuticals, agrochemicals, dyes, and other organic compounds. Its applications span across multiple industries, making it a valuable compound for researchers and manufacturers in the chemical and pharmaceutical sectors.

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  • 53641-60-4 Structure
  • Basic information

    1. Product Name: 2-PHENYLGLYCINONITRILE HYDROCHLORIDE
    2. Synonyms: 2-amino-2-phenylacetonitrilehydrochloride;aminophenyl-acetonitrilhydrochloride;ALPHA-AMINOBENZYL CYANIDE HYDROCHLORIDE;ALPHA-AMINOPHENYLACETONITRILE HYDROCHLORIDE;ALPHA-PHENYLGLYCINONITRILE HYDROCHLORIDE;(+/-)-2-PHENYLGLYCINONITRILE HYDROCHLORIDE;2-PHENYLGLYCINONITRILE HYDROCHLORIDE;TIMTEC-BB SBB003872
    3. CAS NO:53641-60-4
    4. Molecular Formula: C8H8N2*ClH
    5. Molecular Weight: 168.62
    6. EINECS: 258-680-1
    7. Product Categories: N/A
    8. Mol File: 53641-60-4.mol
  • Chemical Properties

    1. Melting Point: 164-165 °C (dec.)(lit.)
    2. Boiling Point: 235.8°Cat760mmHg
    3. Flash Point: 96.4°C
    4. Appearance: /
    5. Density: g/cm3
    6. Vapor Pressure: 0.0491mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. BRN: 4155088
    11. CAS DataBase Reference: 2-PHENYLGLYCINONITRILE HYDROCHLORIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-PHENYLGLYCINONITRILE HYDROCHLORIDE(53641-60-4)
    13. EPA Substance Registry System: 2-PHENYLGLYCINONITRILE HYDROCHLORIDE(53641-60-4)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 36/38-36/37/38-20/21/22
    3. Safety Statements: 26-37/39
    4. RIDADR: 3439
    5. WGK Germany: 3
    6. RTECS: AL7820000
    7. HazardClass: 6.1
    8. PackingGroup: III
    9. Hazardous Substances Data: 53641-60-4(Hazardous Substances Data)

53641-60-4 Usage

Uses

Used in Pharmaceutical Industry:
2-Phenylglycinonitrile hydrochloride is used as a building block for the synthesis of various drugs and pharmaceutical intermediates. Its role in the development of new medications and the improvement of existing ones is crucial, as it contributes to the advancement of healthcare and the treatment of various diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Phenylglycinonitrile hydrochloride serves as an intermediate in the production of agrochemicals. Its use in this industry helps in the development of effective solutions for crop protection and pest control, ensuring food security and sustainable agriculture.
Used in Dye Manufacturing:
2-Phenylglycinonitrile hydrochloride is utilized in the manufacturing of dyes, contributing to the production of a wide range of colorants used in various applications, such as textiles, plastics, and printing inks. Its presence in this industry highlights its versatility and the diverse range of products it can be involved in.
Used in Organic Compounds Synthesis:
As a key intermediate, 2-Phenylglycinonitrile hydrochloride is employed in the synthesis of other organic compounds. Its ability to participate in various chemical reactions allows for the creation of new compounds with potential applications in different industries, further expanding its utility and significance in the chemical sector.

Check Digit Verification of cas no

The CAS Registry Mumber 53641-60-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,4 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 53641-60:
(7*5)+(6*3)+(5*6)+(4*4)+(3*1)+(2*6)+(1*0)=114
114 % 10 = 4
So 53641-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2.ClH/c9-6-8(10)7-4-2-1-3-5-7;/h1-5,8H,10H2;1H

53641-60-4 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (L06355)  alpha-Phenylglycinonitrile hydrochloride, tech. 85%   

  • 53641-60-4

  • 5g

  • 467.0CNY

  • Detail
  • Aldrich

  • (P25558)  2-Phenylglycinonitrilehydrochloride  technical grade

  • 53641-60-4

  • P25558-5G

  • 587.34CNY

  • Detail
  • Aldrich

  • (P25558)  2-Phenylglycinonitrilehydrochloride  technical grade

  • 53641-60-4

  • P25558-25G

  • 2,633.67CNY

  • Detail

53641-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-PHENYLGLYCINONITRILE HYDROCHLORIDE

1.2 Other means of identification

Product number -
Other names 2-amino-2-phenylacetonitrile hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53641-60-4 SDS

53641-60-4Relevant articles and documents

Gold-catalyzed [3+2]-annulations of α-aryl diazonitriles with ynamides and allenamides to yield 1-amino-1H-indenes

Singh, Rahulkumar Rajmani,Pawar, Samir Kundlik,Huang, Min-Jie,Liu, Rai-Shung

supporting information, p. 11434 - 11437 (2016/09/23)

Gold-catalyzed [3+2]-annulations of α-aryl diazonitriles with ynamides and allenamides yield 1-amino-1H-indenes in two distinct pathways; the success of these annulations relies on the high electrophilicity of α-cyano arylgold carbenes to activate an ionic pathway.

Preparation of α-aminothioamides from aldehydes

Paventi, Martino,Edward, John T.

, p. 282 - 289 (2007/10/02)

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied.Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occuring α-amino acids.The possible pre-biotic significance of these compounds is discussed.

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