54970-72-8

Basic information

• Product Name: Sodium 3,5-chloro-6-hydroxybenzenesulfonate
• Synonyms: DHBS;LABOTEST-BB LT00454586;HDCBS;HDCBS NA;HDCBS, SODIUM SALT;6-HDC;3,5-DICHLORO-2-HYDROXYBENZENESULFONIC ACID SODIUM SALT;3,5-DICHLORO-2-HYDROXYBENZENESULFPHONIC ACID SODIUM SALT
• CAS NO: 54970-72-8
• Molecular Formula: C₆H₃Cl₂O₄S*Na
• Molecular Weight: 265.05
• EINECS: 259-416-8
• Product Categories: API intermediates;Enzyme substrates;buffer
• Mol File: 54970-72-8.mol

Chemical Properties

• Melting Point: >300°C
• Appearance: white to off-white powder
• Storage Temp.: Store at RT.
• Solubility: H2O: 50 mg/mL, clear, colorless
• Sensitive: Hygroscopic
• BRN: 3640643
• CAS DataBase Reference: Sodium 3,5-chloro-6-hydroxybenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 3,5-chloro-6-hydroxybenzenesulfonate(54970-72-8)
• EPA Substance Registry System: Sodium 3,5-chloro-6-hydroxybenzenesulfonate(54970-72-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 54970-72-8(Hazardous Substances Data)

Usage

Uses

Used in Enzymatic Reactions:
Sodium 3,5-chloro-6-hydroxybenzenesulfonate is used as a chromogenic quantitation agent for peroxidase in coupled enzymatic reactions. It is used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) to measure the generation of hydrogen peroxide, which is an essential step in various biochemical processes.
Used in Automated Systems:
In the medical and diagnostic industry, Sodium 3,5-chloro-6-hydroxybenzenesulfonate is used as a component of the Trinder reagent. This reagent is employed with peroxidase to measure the generation of hydrogen peroxide in automated systems, facilitating the efficient and accurate assessment of certain biochemical parameters.
Used in Uric Acid Quantitation:
Sodium 3,5-chloro-6-hydroxybenzenesulfonate is also utilized in the quantitation of uric acid in serum and urine samples. This application is particularly relevant in the field of clinical chemistry, where the measurement of uric acid levels can provide valuable information about a patient's health, including the presence of conditions such as gout or kidney dysfunction.

InChI:InChI=1/C6H4Cl2O4S/c7-3-1-4(8)6(9)5(2-3)13(10,11)12/h1-2,9H,(H,10,11,12)/p-1

Upstream product

• 120-83-2 2,4-dichlorophenol 
• 23378-88-3 3,5-dichloro-2-hydroxybenzenesulfonyl chloride 

Downstream Products

• 885127-22-0 [C₆H₂(3,5-Cl₂)(2-OTl)(SO₃Na)] 

Relevant articles and documents

Synthetic method of 3,5-dichloro sodium phenolsulfonate

The invention provides an economic and environment-friendly synthetic method of 3,5-dichloro sodium phenolsulfonate. The method comprises the steps that 2,4-chlorophenesic acid is adopted as a raw material, fuming sulphuric acid/chlorosulfonic acid/thionyl chloride is adopted as a sulfonating agent for a reaction, after the reaction is finished, extraction is performed, and then neutralization is performed with sodium carbonate to obtain 3,5-dichloro sodium phenolsulfonate. The production technology is small in waste acid generation amount, clean, environmentally friendly, high in yield and low in cost.