5614-53-9 Usage
Uses
Used in Pharmaceutical Industry:
Theophylline Impurity 1 is used as an impurity in the production of Theophylline, a medication with diuretic, cardiac stimulant, and smooth muscle relaxant activities. The presence of this impurity can affect the overall efficacy and safety of the drug, making it important to monitor and control its levels during the manufacturing process.
Used in Research and Development:
Theophylline Impurity 1 is used as a research compound for studying the effects of impurities on the pharmacological properties of Theophylline. Understanding the role of this impurity can help in the development of more effective and safer medications with improved therapeutic profiles.
Used in Quality Control:
Theophylline Impurity 1 is used in quality control processes to ensure the purity and safety of Theophylline-based medications. By monitoring the levels of this impurity, manufacturers can maintain the quality and consistency of their products, ensuring that they meet regulatory standards and provide the desired therapeutic effects to patients.
Check Digit Verification of cas no
The CAS Registry Mumber 5614-53-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,1 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5614-53:
(6*5)+(5*6)+(4*1)+(3*4)+(2*5)+(1*3)=89
89 % 10 = 9
So 5614-53-9 is a valid CAS Registry Number.
5614-53-9Relevant academic research and scientific papers
Synthesis of new 7-alkylated theophyllines by chemical modification of dyphylline
El Ashry, El Sayed H.,Rashed, Nagwa,Awad, Laila F.,Abdel-Rahman, Adel A. H.,Rasheed, Hanna A.
, p. 440 - 450 (2007/10/03)
Acetylation of 7-(2,3-dihydroxyprop-1-yl)theophylline (1) afforded the di-O-acetyl derivative 2. Reaction of 1 with acetone and benzaldehyde gave the 1,3-dioxolane derivatives 4 and 5, respectively. Periodate oxidation of 1 gave theophylline-7-acetaldehyde (6). Treatment of 6 with hydroxylamine hydrochloride, thiosemicarbazide and benzoylhydrazine afforded the corresponding oxime 9, thiosemicarbazone 10 and benzoylhydrazone 11. Treatment of 10 and 11 with boiling acetic anhydride afforded the respective 1,3,4-thiadiazoline 12 and oxadiazoline 13. Condensation of 6 with dimedone followed by boiling with dilute hydrochloric acid afforded the xanthene derivative 15.
