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5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE is a chemical compound that acts as a substrate for the enzyme 5'-nucleotide phosphodiesterase, which catalyzes the hydrolysis of the phosphodiester bond within a 5'-nucleotide, leading to the release of a phosphate group and the formation of a nucleotide with a free 5'-hydroxyl group.

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  • 57072-35-2 Structure
  • Basic information

    1. Product Name: 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE
    2. Synonyms: 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE;o-4-nitrophenylphenylphosphonate;P-nitrophenyl phenylphosphonate free*acid crystal;P-NITROPHENYL PHENYLPHOSPHONATE FREE*ACI D CRYSTALLI;4-nitrophenyl phenylphosphonate;4-Nitrophenyl hydrogen phenylphosphonate;Phosphonic acid,P-phenyl-, Mono(4-nitrophenyl) ester;4-Nitrophenyl phenylphosphonat
    3. CAS NO:57072-35-2
    4. Molecular Formula: C12H10NO5P
    5. Molecular Weight: 279.19
    6. EINECS: N/A
    7. Product Categories: Phosphodiesterase, 5μ-Nucleotide;Enzyme Substrates;Substrates by Enzyme
    8. Mol File: 57072-35-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 465.4°Cat760mmHg
    3. Flash Point: 235.2°C
    4. Appearance: /
    5. Density: 1.45g/cm3
    6. Vapor Pressure: 1.85E-09mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. PKA: 1.86±0.58(Predicted)
    11. CAS DataBase Reference: 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE(57072-35-2)
    13. EPA Substance Registry System: 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE(57072-35-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 57072-35-2(Hazardous Substances Data)

57072-35-2 Usage

Uses

Used in Enzymatic Assays:
5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE is used as a substrate in enzymatic assays for studying the activity of 5'-nucleotide phosphodiesterase and for screening potential inhibitors or activators of the enzyme.
Used in Biochemical Research:
In the field of biochemical research, 5'-NUCLEOTIDE PHOSPHODIESTERASE SUBSTRATE is utilized to investigate the mechanisms and kinetics of nucleotide hydrolysis, providing insights into the fundamental processes of nucleotide metabolism and enzyme function.

Check Digit Verification of cas no

The CAS Registry Mumber 57072-35-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,0,7 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 57072-35:
(7*5)+(6*7)+(5*0)+(4*7)+(3*2)+(2*3)+(1*5)=122
122 % 10 = 2
So 57072-35-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H10NO5P/c14-13(15)10-6-8-11(9-7-10)18-19(16,17)12-4-2-1-3-5-12/h1-9H,(H,16,17)/p-1

57072-35-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-nitrophenoxy)-phenylphosphinic acid

1.2 Other means of identification

Product number -
Other names phenylphosphonic acid bis-(4-nitrophenyl)-ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57072-35-2 SDS

57072-35-2Relevant articles and documents

Hydrolysis of Some Chromogenic Substrates and Adenosine Triphosphate Catalyzed by Phosphodiesterase-phosphomonoesterase from Fusarium moniliforme

Yoshida, Hiroshi,Kawai, Masayuki,Okimura, Chiseko,Hirama, Nobuyuki,Konno, Osamu

, p. 549 - 553 (2007/10/02)

For comparison with known phosphodiesterases, the mode of action of phosphodiesterase-phosphomonoesterase from Fusarium moniliforme toward some key substrates was examined.The enzyme catalyzed the hydrolysis of either thymidine 3'-(4-nitrophenylphosphate)

PHOSPHONATE MONOESTERS AND METHOD OF PREPARATION

-

, (2008/06/13)

Synthesis of phosphonate monoesters, as well as the use of such monoesters as substrates for enzymes which normally hydrolyze phosphodiester linkages, and a method for distinguishing between Type I and Type II phosphodiesterase enzymes using such monoeste

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