57235-35-5

Basic information

• Product Name: 2-Mercapto-4,6-dimethoxypyrimidine
• Synonyms: PYRIMIDINE, 4,6-DIMETHOXY-2-(METHYLTHIO)-;4,6-DIMETHOXY-2-THIOMETHYLPYRIMIDINE;4,6-DIMETHOXY-2-METHYLMERCAPTO PYRIMIDINE;4,6-DIMETHOXY-2-METHYLMERCAPYRIMIDINE;2-Mercapto-4,6-Dimethoxy-Pyrimidine;2(1H)-PYRIMIDINETHIONE,4,6-DIMETHOXY;4,6-Dimethoxy-2-mercaptopyrimidine
• CAS NO: 57235-35-5
• Molecular Formula: C₆H₈N₂O₂S
• Molecular Weight: 172.2
• Mol File: 57235-35-5.mol

Chemical Properties

• Melting Point: 56-60 °C(lit.)
• Boiling Point: 250.9oC at 760 mmHg
• Flash Point: 105.6oC
• Appearance: /
• Density: 1.32g/cm3
• Vapor Pressure: 0.0211mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.11±0.10(Predicted)
• CAS DataBase Reference: 2-Mercapto-4,6-dimethoxypyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Mercapto-4,6-dimethoxypyrimidine(57235-35-5)
• EPA Substance Registry System: 2-Mercapto-4,6-dimethoxypyrimidine(57235-35-5)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 57235-35-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Mercapto-4,6-dimethoxypyrimidine is used as a key intermediate for the synthesis of various pharmaceuticals, leveraging its bioactive properties to develop new drugs with potential antifungal, antibacterial, and anti-inflammatory effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Mercapto-4,6-dimethoxypyrimidine is utilized as a building block for the creation of novel agrochemicals, contributing to the development of effective and environmentally friendly products for agricultural use.
Used as a Corrosion Inhibitor:
2-Mercapto-4,6-dimethoxypyrimidine is employed as a corrosion inhibitor, taking advantage of its chemical properties to protect materials from degradation in various industrial applications.
Used as an Antioxidant in Polymer Materials:
MDP is used as an antioxidant in polymer materials, enhancing the stability and longevity of these materials by preventing oxidative degradation.

InChI:InChI=1/C6H8N2O2S/c1-9-4-3-5(10-2)8-6(11)7-4/h3H,1-2H3,(H,7,8,11)

Upstream product

• 13223-25-1 2-chloro-4,6-dimethoxypyrimidine 
• 35144-22-0 4,6-dimethyl-2-methylsulfonylpyrimidine 
• 113583-35-0 4,6-dimethoxypyrimidin-2-yl methyl sulfone 

Downstream Products

• 1334214-42-4 C₂₂H₂₄N₆O₂S 
• 90905-46-7 4,6-dimethoxy-2-(methylsulfanyl)pyrimidine 
• 123342-93-8 2-chloro-6-[(4,6-dimethoxypyrimidin-2-yl)thio]benzoic acid 
• 170296-17-0 methyl 3-benzyloxy-3-phenyl-2-(4,6-dimethoxypyrimidin-2-ylthio)-butyrate 

Relevant articles and documents

7-(4,6-dimethoxypyrimidinyl)oxy- and -thiophthalides as novel herbicides: Part 1. CGA 279 233: A new grass-killer for rice

A series of novel types of 7-(4,6-dimethoxypyrimidin-2-yl)oxy - and -thio-3-methyl-1 (3H)-isobenzofuranones were discovered at Dr R Maag AG. From the thio-isobenzofuranyl series, CGA 279 233 - BSI-proposed common name pyriftalid - was chosen for further development as a grass herbicide for use in rice. General synthetic approaches to these new phthalic acid-derived compounds are given, with emphasis on the synthesis of pyriftalid and its physico-chemical behaviour.

Pyrimidinylthioacrylic acid derivatives useful as herbicides

The present invention relates to novel pyrimidinylthioacrylic acid derivatives of the formula (I) wherein R1represents hydrogen or in each case optionally substituted C1 6 alkyl, C2 4 alkenyl or C2 4 alkynyl, R2represents hydrogen or optionally substituted C1 6 alkyl, or alkali salts, R3 and R4each independently represent C1 4 alkyl, C1 4 alkoxy, halogeno-C1 4 alkyl, halogeno-C1 4 alkoxy or halogen, and R5represents hydrogen, or in each case optionally substituted C1 6 alkyl, phenyl, C2 4 alkenyl, C2 4 alkynyl, or a heterocyclic ring, or an alkali metal salt, alkali earth metal or organic ammonium salt of pyrimidinylthioacrylic acid derivatives of the formula (I), to processes for their preparation and their use as herbicides, as well as to novel intermediates and to a process for their preparation.