58164-02-6

Basic information

• Product Name: 1-IODO-3-TERT-BUTYLBENZENE
• Synonyms: 3-(tert-Butyl)iodobenzene
• CAS NO: 58164-02-6
• Molecular Formula: C₁₀H₁₃I
• Molecular Weight: 260.12
• Mol File: 58164-02-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 244.6°Cat760mmHg
• Flash Point: 107°C
• Appearance: /
• Density: 1.459g/cm³
• CAS DataBase Reference: 1-IODO-3-TERT-BUTYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-3-TERT-BUTYLBENZENE(58164-02-6)
• EPA Substance Registry System: 1-IODO-3-TERT-BUTYLBENZENE(58164-02-6)

Safety Data

• Hazardous Substances Data: 58164-02-6(Hazardous Substances Data)

Usage

General Description

1-Iodo-3-tert-butylbenzene is a chemical compound with the molecular formula C10H13I. It is a derivative of benzene, with an iodine atom attached to the 1 position and a tert-butyl group attached to the 3 position. 1-IODO-3-TERT-BUTYLBENZENE is commonly used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It is a colorless to pale yellow liquid with a strong odor, and it is highly flammable. 1-Iodo-3-tert-butylbenzene is also known for its potential health hazards, as it may cause skin and eye irritation, and it is harmful if swallowed or inhaled. Therefore, it should be handled with caution and in accordance with proper safety measures.

Upstream product

• 2142-70-3 2-iodoacetophenone 
• 544-97-8 dimethyl zinc(II) 
• 14452-30-3 3'-iodoacetophenone 
• 5369-19-7 3-tert-butylaniline 

Downstream Products

• 861858-30-2 1-benzyl-3-(3-tert-butyl-phenyl)-piperidin-3-ol 
• 94572-90-4 1-(3-tert-butyl-phenyl)-cyclohexanol 
• 861857-72-9 2-methyl-propane-2-sulfinic acid [8-(3-tert-butyl-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-amide 
• 1110656-21-7 4-(3-(tert-butyl)phenyl)pyridine 
• 111220-30-5 1-(tert-butyl)-3-iodo-5-methylbenzene 
• 84736-47-0 4-(4-(tert-butyl)phenyl)morpholine 

Relevant articles and documents

SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS

The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INHIBITORS

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES

Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s disease and other diseases characterized by deposition of A beta peptide in a mammal.