58164-02-6

Basic information

• Product Name: 1-IODO-3-TERT-BUTYLBENZENE
• Synonyms: 3-(tert-Butyl)iodobenzene
• CAS NO: 58164-02-6
• Molecular Formula: C₁₀H₁₃I
• Molecular Weight: 260.12
• Mol File: 58164-02-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 244.6°Cat760mmHg
• Flash Point: 107°C
• Appearance: /
• Density: 1.459g/cm³
• CAS DataBase Reference: 1-IODO-3-TERT-BUTYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-3-TERT-BUTYLBENZENE(58164-02-6)
• EPA Substance Registry System: 1-IODO-3-TERT-BUTYLBENZENE(58164-02-6)

Safety Data

• Hazardous Substances Data: 58164-02-6(Hazardous Substances Data)

Usage

Description

1-IODO-3-TERT-BUTYLBENZENE, with the molecular formula C10H13I, is a chemical compound derived from benzene. It features an iodine atom at the 1 position and a tert-butyl group at the 3 position. This colorless to pale yellow liquid, characterized by a strong odor and high flammability, is utilized as a reagent in organic synthesis. It plays a significant role in the preparation of pharmaceuticals and agrochemicals, despite its potential health hazards, which include skin and eye irritation and harmful effects if ingested or inhaled.

Uses

Used in Pharmaceutical Industry:
1-IODO-3-TERT-BUTYLBENZENE is used as a synthetic reagent for the production of various pharmaceuticals. Its unique structure allows for the creation of a wide range of medicinal compounds, contributing to the development of new treatments and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 1-IODO-3-TERT-BUTYLBENZENE is employed as a reagent in the synthesis of different agrochemicals. It aids in the development of products designed to enhance crop protection and improve agricultural yields.
It is important to handle 1-IODO-3-TERT-BUTYLBENZENE with care due to its potential health risks, ensuring that proper safety measures are followed to minimize exposure and protect individuals involved in its use and production.

Upstream product

• 2142-70-3 2-iodoacetophenone 
• 544-97-8 dimethyl zinc(II) 
• 14452-30-3 3'-iodoacetophenone 
• 5369-19-7 3-tert-butylaniline 

Downstream Products

• 861858-30-2 1-benzyl-3-(3-tert-butyl-phenyl)-piperidin-3-ol 
• 94572-90-4 1-(3-tert-butyl-phenyl)-cyclohexanol 
• 861857-72-9 2-methyl-propane-2-sulfinic acid [8-(3-tert-butyl-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-amide 
• 1110656-21-7 4-(3-(tert-butyl)phenyl)pyridine 
• 111220-30-5 1-(tert-butyl)-3-iodo-5-methylbenzene 
• 84736-47-0 4-(4-(tert-butyl)phenyl)morpholine 

Relevant articles and documents

SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS

The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INHIBITORS

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES

Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s disease and other diseases characterized by deposition of A beta peptide in a mammal.