1-IODO-3-TERT-BUTYLBENZENE

Base Information

• Chemical Name: 1-IODO-3-TERT-BUTYLBENZENE
• CAS No.: 58164-02-6
• Molecular Formula: C10H13I
• Molecular Weight: 260.118
• Mol file: 58164-02-6.mol

Synonyms:3-(tert-Butyl)iodobenzene

Chemical Property of 1-IODO-3-TERT-BUTYLBENZENE

Chemical Property:

• Refractive Index: 1.559
• Boiling Point: 244.6°Cat760mmHg
• Flash Point: 107°C
• PSA: 0.00000
• Density: 1.459g/cm³
• LogP: 3.58870

Purity/Quality:

98.5% ^*data from raw suppliers

1-tert-Butyl-3-Iodobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-IODO-3-TERT-BUTYLBENZENE

There total 4 articles about 1-IODO-3-TERT-BUTYLBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-tert-butylaniline (5369-19-7) → 1-(tert-butyl)-3-iodobenzene (58164-02-6)

Guidance literature:

3-tert-butylaniline; With hydrogenchloride; sodium nitrite; In water; at 2 ℃; for 0.5h;

With potassium iodide; In water; at 20 ℃;

Reference yield: 76.0%

3'-iodoacetophenone (14452-30-3) + dimethyl zinc(II) (544-97-8) → 1-(tert-butyl)-3-iodobenzene (58164-02-6)

Guidance literature:

With titanium tetrachloride; In dichloromethane; toluene; at -40 - 0 ℃; for 3h;

Reference yield: 76.0%

2-iodoacetophenone (2142-70-3) + dimethyl zinc(II) (544-97-8) → 1-(tert-butyl)-3-iodobenzene (58164-02-6)

Guidance literature:

dimethyl zinc(II); With titanium tetrachloride; In dichloromethane; toluene; at -40 ℃; for 0.166667h;

2-iodoacetophenone; at -40 - 0 ℃; for 3h;

upstream raw materials:

3-tert-butylaniline

3'-iodoacetophenone

dimethyl zinc(II)

2-iodoacetophenone

Downstream raw materials:

1-benzyl-3-(3-tert-butyl-phenyl)-piperidin-3-ol

1-(3-tert-butyl-phenyl)-cyclohexanol

2-methyl-propane-2-sulfinic acid [8-(3-tert-butyl-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-amide

m-t-butylphenyl propionaldehyde