586967-19-3

Basic information

• Product Name: Propanoic acid, 2-methyl-, 1-(1-naphthalenyl)ethyl ester
• CAS NO: 586967-19-3
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• Mol File: 586967-19-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-, 1-(1-naphthalenyl)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-, 1-(1-naphthalenyl)ethyl ester(586967-19-3)
• EPA Substance Registry System: Propanoic acid, 2-methyl-, 1-(1-naphthalenyl)ethyl ester(586967-19-3)

Safety Data

• Hazardous Substances Data: 586967-19-3(Hazardous Substances Data)

Upstream product

• 57605-95-5 1-(1-naphthyl)ethanol 
• 97-72-3 2-Methylpropionic anhydride 
• 794-94-5 p-Methoxybenzoic anhydride 
• 76700-83-9 3-5-dimethoxybenzoic anhydride 
• 94611-94-6 3-methoxybenzoic acid anhydride 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 19820-59-8 benzoic isobutyric anhydride 

Downstream Products

• 15914-84-8 (S)-1-(1-Naphthyl)ethanol 
• 42177-25-3 (R)-1-(naphth-1-yl)ethanol 

Relevant articles and documents

Catalytic parallel kinetic resolution under homogeneous conditions

(Figure Presented) Two complementary chiral catalysts, the phosphine 8d and the DMAP-derived ent-23b, are used simultaneously to selectively activate a mixture of two different achiral anhydrides as acyl donors under homogeneous conditions. The resulting activated intermediates 25 and 26 react with the racemic benzylic alcohol 5 to form enantioenriched esters (R)-24 and (S)-17 by fully catalytic parallel kinetic resolution (PKR). The aroyl ester (R)-24 is obtained with near-ideal enantioselectivity for the PKR process, but (S)-17 is contaminated by ca. 8% of the minor enantiomer (R)-17 resulting from a second pathway via formation of mixed anhydride 27 and its activation by 8d.