57605-95-5

Basic information

• Product Name: 1-(1-NAPHTHYL)ETHANOL
• Synonyms: ALPHA-METHYL-1-NAPHTHALENEMETHANOL;ALPHA-NAPHTHYL METHYL CARBINOL;A-NAPHTHYLMETHYLCARBINOL;1-(1-HYDROXYETHYL)NAPHTHALENE;(+/-)-1-(1-NAPHTHYL)ETHANOL;1-(1-NAPHTHYL)ETHANOL;AURORA KA-6960;(+ -)-1-(1-NAPHTHYL)ETHANOL 99%
• CAS NO: 57605-95-5
• Molecular Formula: C₁₂H₁₂O
• Molecular Weight: 172.22
• EINECS: 216-172-7
• Mol File: 57605-95-5.mol
• Article Data: 130

Chemical Properties

• Melting Point: 63-65 °C
• Boiling Point: 262.55°C (rough estimate)
• Appearance: /
• Density: 1.1190
• Refractive Index: 1.6188 (estimate)
• CAS DataBase Reference: 1-(1-NAPHTHYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-NAPHTHYL)ETHANOL(57605-95-5)
• EPA Substance Registry System: 1-(1-NAPHTHYL)ETHANOL(57605-95-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 57605-95-5(Hazardous Substances Data)

Usage

General Description

1-(1-Naphthyl)ethanol, also known as 1-naphthylethanol or 1-naphthylcarbinol, is a colorless crystalline compound that belongs to the family of naphthyl alcohols. It is derived from naphthalene and is commonly used as a reagent in organic synthesis and as a flavoring agent in the food industry. It has a floral, sweet, and somewhat spicy odor, making it popular in the production of perfumes and fragrances. In addition, it has applications in the pharmaceutical industry as a precursor to the synthesis of various drugs and active pharmaceutical ingredients. 1-(1-Naphthyl)ethanol is also known for its anti-inflammatory and anti-cancer properties, which have attracted interest in medical research and drug development. Overall, it is a versatile compound with various industrial, commercial, and medicinal applications.

Upstream product

• 941-98-0 1'-naphthacetophenone 
• 66-77-3 1-naphthaldehyde 
• 83469-34-5 1-<(methoxytrimethylsilyl)methyl>naphthalene 
• 83469-36-7 4-methoxy-1-<(methoxytrimethylsilyl)methyl>naphthalene 
• 1127-76-0 1-ethylnapthelene 
• 557-20-0 diethylzinc 
• 64-17-5 ethanol 
• 90-14-2 1-Iodonaphthalene 
• 57573-90-7 acetic acid 1-(1-naphthyl)ethyl ester 
• 76469-33-5 2-chloro-1-(naphthalen-1-yl)ethan-1-one 
• 62094-18-2 1-(1’-chloroethyl)naphthalene 
• 703-55-9 1-naphthylmagnesiumbromide 
• 74-83-9 methyl bromide 
• 826-74-4 1-vinylnaphthalene 

Downstream Products

• 15914-84-8 (S)-1-(1-Naphthyl)ethanol 
• 941-98-0 1'-naphthacetophenone 
• 16197-95-8 1-(naphthalen-1-yl)ethyl acetate 
• 875153-28-9 1-(naphthalen-1-yl)ethyl 3-methyl-4-[methyl(phenyl)amino]-4-oxobutanoate 
• 88766-23-8 2-(1-naphthyl)-1-phenylpropane 
• 1127-76-0 1-ethylnapthelene 
• 1172119-67-3 1-(4-chloro-4-phenylbut-3-en-2-yl)naphthalene 
• 1235454-36-0 C₁₉H₂₂O₂ 
• 1245719-50-9 3-(1-(naphthalen-1-yl)ethoxy)-1-phenylbutan-1-one 
• 5751-27-9 1-(1-naphthalenyl)-3-phenylpropan-1-ol 
• 232923-59-0 (1R)-1-(naphthalen-1-yl)ethyl 2-methylpropanoate 
• 909906-66-7 benzyl (1-(naphthalen-1-yl)ethyl)carbamate 
• 826-74-4 1-vinylnaphthalene 
• 62094-18-2 1-(1’-chloroethyl)naphthalene 

Relevant articles and documents

Manganese-catalyzed homogeneous hydrogenation of ketones and conjugate reduction of α,β-unsaturated carboxylic acid derivatives: A chemoselective, robust, and phosphine-free in situ-protocol

We communicate a user-friendly and glove-box-free catalytic protocol for the manganese-catalyzed hydrogenation of ketones and conjugated C[dbnd]C[sbnd]bonds of esters and nitriles. The respective catalyst is readily assembled in situ from the privileged [Mn(CO)5Br] precursor and cheap 2-picolylamine. The catalytic transformations were performed in the presence of t-BuOK whereby the corresponding hydrogenation products were obtained in good to excellent yields. The described system offers a brisk and atom-efficient access to both secondary alcohols and saturated esters avoiding the use of oxygen-sensitive and expensive phosphine-based ligands.

Selective C-alkylation Between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum

The first implementation of a molybdenum complex with an easily accessible bis-N-heterocyclic carbene ligand to catalyze β-alkylation of secondary alcohols via borrowing-hydrogen (BH) strategy using alcohols as alkylating agents is reported. Remarkably high activity, excellent selectivity, and broad substrate scope compatibility with advantages of catalyst usage low to 0.5 mol%, a catalytic amount of NaOH as the base, and H2O as the by-product are demonstrated in this green and step-economical protocol. Mechanistic studies indicate a plausible outer-sphere mechanism in which the alcohol dehydrogenation is the rate-determining step.

Achiral and chiral NNN-pincer nickel complexes with oxazolinyl backbones: application in transfer hydrogenation of ketones

We describe the synthesis of new NNN-oxazolinyl-pincer nickel complexes and their application in the transfer hydrogenation of ketones. Achiral NNN-ligands, R′2-oxazolinyl-2-C6H4-NH-C(O)CH2NEt2[(