60093-15-4

Basic information

• Product Name: 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE
• Synonyms: 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE
• CAS NO: 60093-15-4
• Molecular Formula: C₈H₈N₄S
• Molecular Weight: 192.24
• Mol File: 60093-15-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 210-212°C
• Boiling Point: 375.7 °C at 760 mmHg
• Flash Point: 181 °C
• Appearance: /
• Density: 1.438 g/cm³
• PKA: 3.85±0.11(Predicted)
• CAS DataBase Reference: 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE(60093-15-4)
• EPA Substance Registry System: 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE(60093-15-4)

Safety Data

• Hazardous Substances Data: 60093-15-4(Hazardous Substances Data)

Usage

General Description

3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE is a heterocyclic organic compound with the molecular formula C8H7N5S. It is a yellow crystalline solid that is used in the synthesis of pharmaceuticals and agrochemicals. The compound contains a thiadiazole ring with an amino group at the 3-position and a phenylamino group at the 5-position. It has a variety of potential applications in medicinal chemistry, including as a building block in the development of new therapeutic agents. Additionally, 3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE has demonstrated potential antitumor and antiviral activities, making it a subject of interest in drug discovery research.

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 15989-47-6 1-phenyl-3-guanylthiourea 

Downstream Products

• 104424-07-9 N-(2-benzoyl-3-benzoylimino-2,3-dihydro-[1,2,4]thiadiazol-5-yl)-N-phenyl-benzamide 
• 97149-64-9 5-anilino-3-(N'-benzoylureido)-1,2,4-thiadiazole 
• 2254-85-5 (3-chloro-[1,2,4]thiadiazol-5-yl)-phenyl-amine 
• 91688-32-3 N-(3-acetylamino-[1,2,4]thiadiazol-5-yl)-N-phenyl-acetamide 
• 93647-51-9 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-3-nitro-benzenesulfonamide 
• 107101-21-3 N-phenyl-N-[2-(toluene-sulfonyl)-3-(toluene-4-sulfonylimino)-2,3-dihydro-[1,2,4]thiadiazol-5-yl]-toluene-4-sulfonamide 
• 93734-57-7 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-toluene-4-sulfonamide 
• 54356-29-5 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-benzamide 
• 97283-87-9 N-(2-acetyl-3-acetylimino-2,3-dihydro-[1,2,4]thiadiazol-5-yl)-N-phenyl-acetamide 

Relevant articles and documents

Co-Catalyzed Intramolecular S-N Bond Formation in Water for 1,2-Benzisothiazol-3(2H)-ones and 1,2,4-Thiadiazoles Synthesis

An efficient and versatile Co-catalyzed intramolecular S-N bond formation in water to synthesize 1,2-benzisothiazol-3(2H)-one and 1,2,4-thiadiazoles derivatives in good to excellent yields was developed. The transformation showed great tolerance with a broad range of substituents. The mother liquor was able to be recycled 6 times with minor loss in product yield.

A facile synthesis of novel nitrogen-sulphur heterocycles containing the amidino moiety and their antimicrobial activity - Part I

The interaction of amidinothiocarbamide 1 and 4-bromo-1,3-substituted-pyrazol-5-ones 1 afford 2-guanidino-4, 6-substituted-pyrazolo [5,4-d]thiazoles 5 on reaction with aldehydes yield the corresponding schiff's bases bases 6. An alternate unambiguous one