6280-96-2

Basic information

• Product Name: 2-Propoxyphenol
• Synonyms: o-propoxyphenol;2-n-Propoxyphenol;2-Propoxyphenol
• CAS NO: 6280-96-2
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19038
• EINECS: 228-484-0
• Mol File: 6280-96-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 227°C (estimate)
• Flash Point: 97.2 °C
• Appearance: white to beige crystal
• Density: 1.0523
• Vapor Pressure: 0.0486mmHg at 25°C
• Refractive Index: 1.5176 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.72±0.30(Predicted)
• Water Solubility: 2.359g/L(24.99 oC)
• CAS DataBase Reference: 2-Propoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propoxyphenol(6280-96-2)
• EPA Substance Registry System: 2-Propoxyphenol(6280-96-2)

Safety Data

• Hazardous Substances Data: 6280-96-2(Hazardous Substances Data)

Usage

General Description

2-Propoxyphenol, also known as propofol, is a chemical compound commonly used as a general anesthetic. It is a white, crystalline substance with a slightly sweet odor and is typically administered intravenously to induce and maintain anesthesia during surgeries or medical procedures. 2-Propoxyphenol acts as a sedative and hypnotic agent, producing a rapid onset of anesthesia and a quick recovery time. It works by enhancing the effect of gamma-aminobutyric acid (GABA) in the brain, leading to its sedative and anesthetic effects. Additionally, it has antiemetic properties, which helps prevent nausea and vomiting after surgery. Despite its widespread use in medical settings, propofol also has the potential for abuse and can result in adverse effects such as respiratory depression, low blood pressure, and potential allergic reactions.

InChI:InChI=1/C9H12O2/c1-2-7-11-9-6-4-3-5-8(9)10/h3-6,10H,2,7H2,1H3

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 60-29-7 diethyl ether 
• 95-47-6 o-xylene 
• 29515-39-7 1-methoxy-2-n-propoxybenzene 
• 540-54-5 1-Chloropropane 
• 120-80-9 benzene-1,2-diol 
• 106-94-5 propyl bromide 
• 7664-41-7 ammonia 
• 2606-59-9 2-Propoxy-benzylbromid 
• 90-02-8 salicylaldehyde 
• 1126-20-1 2-allyloxyphenol 
• 274-09-9 Methylenedioxybenzene 
• 107-08-4 1-iodo-propane 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 110943-74-3 4-hydroxy-3-propoxybenzaldehyde 
• 1005005-55-9 2-allyl-6-propoxy phenol 
• 1005005-88-8 (1-allyloxy-2-propoxybenzene) 
• 222031-84-7 2-hydroxy-3-n-propoxybenzaldehyde 
• 1430847-78-1 1-[2-(4-chlorophenyl)-4-(2-propoxyphenoxymethyl)-[1,3]-dioxolan-2-ylmethyl]-1H-[1,2,4]-triazole 

Relevant articles and documents

Direct oxidation of the C(sp2)-C(sp3) bond from benzyltrimethylsilanes to phenols

A novel pathway for direct conversion of benzylsilanes to phenols by oxidation with Na2S2O8 and oxygen is efficiently developed under mild and neutral conditions. The reaction shows good functional group tolerance to afford phenols in moderate yields. The possible mechanism is proposed based on the isotopic labeling trials.

Dialkoxybenzene and dialkoxyallylbenzene feeding and oviposition deterrents against the cabbage looper, trichoplusia ni: Potential insect behavior control agents

The antifeedant, oviposition deterrent, and toxic effects of individual dialkoxybenzene compounds/sets and of hydroxy- or alkoxy-substituted allylbenzenes, obtained through Claisen rearrangement of substituted allyloxybenzenes, were assessed against the cabbage looper, Trichoplusia ni, in laboratory bioassays. Most of the compounds/sets strongly deterred larval feeding, with some exhibiting mild toxic and oviposition deterrent effects as well. Some of the compounds/sets were more active than the commercial insect repellent, DEET (N,N-diethyl-m-toluamide), as both feeding and oviposition deterrents against the cabbage looper. On the basis of the obtained oviposition data a general hypothesis was proposed regarding the oviposition sites: one binding mode with the alkyl and allyl groups on the same side of the benzene ring resulted in deterrence, the other with alkyl and allyl groups on opposite sides of the benzene ring resulted in stimulation. The results suggest some structure-activity relationships useful in improving the efficacy of the compounds and designing new, nontoxic insect control agents for agriculture.

METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar

The invention provides in part dialkoxybenzene and eugenol compounds for controlling infestation by a Lymantria dispar, and methods thereof. The compounds include a compound of Formula I: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; R2 may be at positions 2, 3 or 4 and may be H, methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; and R3 may be optionally present at positions 2, 3 and 4, and is allyl; with the provisos that when R2 is at position 2, R3 if present is at position 3, or when R2 is at to position 3, R3 if present is at positions 2 or 4, or when R2 is at position 4, R3 if present is at position 2; or of Formula II: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; or mixtures thereof.