630128-01-7

Basic information

• Product Name: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate
• Synonyms: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate;Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-methyl 1-(phenylmethyl) ester, (2S)-;2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-hexanedioic acid 6-methyl 1-(phenylmethyl) ester;(S)-1-benzyl 6-methyl 2-((tert-butoxycarbonyl)amino)-4-oxohexanedioate
• CAS NO: 630128-01-7
• Molecular Formula: C₁₉H₂₅NO₇
• Molecular Weight: 379.4043
• EINECS: -0
• Mol File: 630128-01-7.mol

Chemical Properties

• Melting Point: 69-72 °C
• Boiling Point: 517.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.183±0.06 g/cm3(Predicted)
• PKA: 10.21±0.46(Predicted)
• CAS DataBase Reference: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(630128-01-7)
• EPA Substance Registry System: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(630128-01-7)

Safety Data

• Hazardous Substances Data: 630128-01-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the creation of complex molecular structures. Its presence in the synthesis process aids in the development of new drugs with improved efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical sector, Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its role in these syntheses contributes to the development of more effective and environmentally friendly products for agricultural use.
Used in Fine Chemicals Industry:
Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is employed as a building block in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including fragrances, dyes, and flavorings. Its versatility allows for the creation of a wide range of specialty chemicals with specific properties.
Used in Polymer and Material Science:
Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is used in the production of various types of polymers and materials, where it contributes to the development of new materials with unique properties. Its incorporation into polymer structures can enhance characteristics such as strength, flexibility, and chemical resistance, making it valuable in the advancement of material science.

Upstream product

• 844644-72-0 2-tert-butoxycarbonylamino-4-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidene)-4-hydroxy-butyric acid benzyl ester 
• 30925-18-9 2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester 
• 67-56-1 methanol 

Downstream Products

• 1186468-33-6 C₄₃H₇₃NO₁₁SSi₂ 
• 630128-07-3 (4aS,6R,7R,8S,8aR)-7,8-Bis-benzyloxy-3-((S)-2-benzyloxycarbonyl-2-tert-butoxycarbonylamino-ethyl)-6-benzyloxymethyl-4-(2-trimethylsilanyl-ethanesulfonyl)-4,4a,6,7,8,8a-hexahydro-5-oxa-1-thia-4-aza-naphthalene-2-carboxylic acid methyl ester 
• 630128-10-8 (2R,3R,4S,4aR,7S,9aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-oxo-9-(2-trimethylsilanyl-ethanesulfonyl)-2,3,4,4a,5,6,7,8,9,9a-decahydro-1-oxa-10-thia-6,9-diaza-anthracene-7-carboxylic acid benzyl ester 
• 766514-54-9 (4aR,6R,7R,8S,8aR)-3-((S)-2-Amino-2-benzyloxycarbonyl-ethyl)-7,8-bis-benzyloxy-6-benzyloxymethyl-6,7,8,8a-tetrahydro-4aH-4,5-dioxa-1-thia-naphthalene-2-carboxylic acid methyl ester 
• 766514-60-7 (4aR,6R,7R,8S,8aR)-6-Acetoxymethyl-3-((S)-2-acetylamino-2-benzyloxycarbonyl-ethyl)-7,8-bis-benzyloxy-6,7,8,8a-tetrahydro-4aH-4,5-dioxa-1-thia-naphthalene-2-carboxylic acid methyl ester 

Relevant articles and documents

POLYMORPHIC FORM OF COMPOUND, PREPARATION METHOD AND USE THEREOF

The present disclosure relates to polymorphic forms of the compound methyl (3R,6S)-6-amino-sulfonylamino-1-(thiazol-2-yl)-3-(2,3,4-trifluorophenyl)-3,5,6,7-tetrahydropyrrolo[1,2-c]pyrimidin-4-formate (compound 1). The present disclosure further relates to

CRYSTAL FORM, PREPARATION METHOD AND INTERMEDIATE OF DIHYDROPYRIDO RING COMPOUND

Disclosed in the present disclosure are a crystal form of a dihydropyrido ring compound, and preparation method and intermediate thereof.

Synthesis of a Fluorescent-Labeled Bisbenzamidine Containing the Central (6,7-Dimethoxy-4-coumaryl)Alanine Building Block

The synthesis of an amino acid amide is reported, which contains two benzamidine cores, one placed in the amide part the other one within the sulfonyl N-capping group. The amino acid side chain bears the 6,7-dimethoxycoumarin fluorophore. The fluorescent amino acid was prepared by using the von-Pechmann reaction. The two corresponding nitrile groups of a precursor molecule were simultaneously converted to the amidine moieties by the Pinner reaction. The fluorescent properties of the final compound were determined.

A new scaffold for the stereoselective synthesis of α-O-linked glycopeptide mimetics

α-O-Linked glycohomoglutamates are obtained as diastereomerically pure compounds by chemo-, regio-, and stereoselective cycloadditions between glycals and aspartic acid derivatives. The latter constitute orthogonally functionalized scaffolds for glycopept

A novel neoglycopeptide building block

The synthesis of a neoglycopeptide building block is described. The key step is a cycloaddition where the chemistry is orthogonal to standard glycosyl transfer methodology. Also described is some exploratory chemistry of the building block.