64124-21-6

Basic information

• Product Name: Trimelamol
• Synonyms: Trimelamol;[1,3,5-Triazine-2,4,6-triyltris(methylimino)]trismethanol
• CAS NO: 64124-21-6
• Molecular Formula: C₉H₁₈N₆O₃
• Molecular Weight: 258.28
• Mol File: 64124-21-6.mol

Chemical Properties

• Melting Point: 129°C
• Boiling Point: 401.53°C (rough estimate)
• Flash Point: 254.7°C
• Appearance: /
• Density: 1.2424 (rough estimate)
• Vapor Pressure: 1.03E-10mmHg at 25°C
• Refractive Index: 1.8000 (estimate)
• Water Solubility: 9.04g/L(25 oC)
• CAS DataBase Reference: Trimelamol(CAS DataBase Reference)
• NIST Chemistry Reference: Trimelamol(64124-21-6)
• EPA Substance Registry System: Trimelamol(64124-21-6)

Safety Data

• Hazardous Substances Data: 64124-21-6(Hazardous Substances Data)

Usage

Uses

Used in Cosmetics and Personal Care Industry:
Trimelamol is used as a humectant and skin conditioning agent for its ability to enhance skin hydration and texture. It helps maintain the skin's moisture balance, providing a smoother and healthier appearance.
Used in Hair Care Products:
Trimelamol is used as a conditioning agent in hair care products to improve hair manageability and provide nourishment. It helps to reduce frizz and tangles, leaving the hair soft, smooth, and more manageable.
Used in Beauty Products:
Trimelamol is used in various beauty products such as lotions, creams, and serums to enhance the efficacy of other active ingredients. Its moisturizing properties help to improve the overall performance of these formulations, making them more effective in delivering their intended benefits to the skin and hair.

InChI:InChI=1/C9H18N6O3/c1-13(4-16)7-10-8(14(2)5-17)12-9(11-7)15(3)6-18/h16-18H,4-6H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 2827-46-5 2,4,6-tris(methylamino)-1,3,5-triazine 

Downstream Products

• 177498-86-1 N-Benzyloxy-N-(3-{[(4,6-bis-{[3-(acetyl-benzyloxy-amino)-propoxymethyl]-methyl-amino}-[1,3,5]triazin-2-yl)-methyl-amino]-methoxy}-propyl)-acetamide 
• 177498-85-0 N-Benzyloxy-N-(4-{[(4,6-bis-{[4-(acetyl-benzyloxy-amino)-butoxymethyl]-methyl-amino}-[1,3,5]triazin-2-yl)-methyl-amino]-methoxy}-butyl)-acetamide 
• 1307264-08-9 C₁₄H₂₀N₆O 
• 1307264-07-8 C₂₂H₂₈N₆O₂ 
• 1307264-05-6 C₃₀H₃₆N₆O₃ 
• 2827-46-5 2,4,6-tris(methylamino)-1,3,5-triazine 
• 104880-55-9 N²,N⁴-monomethyllol-N²,N⁴,N⁶-trimethylmelamine 
• 104880-54-8 N²,N⁴-dimethylol-N²,N⁴,N⁶-trimethylmelamine 

Relevant articles and documents

Based on amino-triazine for Mannich compounds to stable organic material

Use of one or more amino-triazine based Mannich-compounds and/or their dimers or trimers and/or one or more precondensate therefrom, including special new amino-triazine based Mannich-compounds, as antioxidant and/or UV-stabilizer for organic material, pr

Application of BODIPY-trimethylmelamine conjugate for DNA crosslinking in vitro

The conjugate of the fluorescent dye 4,4,-difluoro-1,3,5,7-tetramethyl-4- bora-3a,4a-diaza-s-indasten-8-propionic acid (BODIPY) with N2,N 4,N6-trimethylmelamine was obtained. This compound was shown to generate covalent crosslinks between DNA strands in vitro in the presence of formaldehyde.

MELAMINE BASED MANNICH-COMPOUNDS AND A PROCESS FOR OBTAINING THE SAME

The present invention relates to Melamine based Mannich compounds of the general formulae (1 )-(12) and a process for synthesizing melamine based Mannich-products products comprising the steps of a) reacting at least one substituted melamine with at least

Framework-reactive siderophore analogs as potential cell-selective drugs. Design and syntheses of trimelamol-based iron chelators

Currently, the role of DNA-directed alkylating agents as potential anticancer/antimicrobial drugs is of wide interest. Most of the alkylating agents used clinically as drugs damage DNA in cells without specificity, and this can lead to undesired toxicity problems. Minimizing serum residence time by targeting the drug to select pathogens or organs might diminish the effects of nonselective reactivity. This paper describes the syntheses and preliminary studies of analogs of siderophores (microbial iron chelators) 2 and 20 that incorporate centers within the siderophore framework capable of generating potent electrophiles (iminium ions), hopefully after directed cellular recognition and uptake. Formation of N-aminals from trimelamol (3) and substituted hydroxamic acid 4 or 5 was critical for the design and synthesis of the targets. In preliminary biological testing, compound 2, a trimelamol-based siderophore analog, was active against Escherichia coli X580, illustrating the therapeutic potential of this new type of siderophore-mediated drug design and delivery.