6459-59-2

Basic information

• Product Name: DL-HISTIDINE MONOHYDROCHLORIDE
• Synonyms: DL-HISTIDINE MONOHYDROCHLORIDE;dl-histidineHCl1-hydrate;DL-Histidine hydrochloride, monohydrate,98%;DL-Histidine hydrochloride;2-aMino-3-(1H-iMidazol-4-yl)propanoic acid hydrochloride hydrate;DL-HISTIDINE MONOHCL
• CAS NO: 6459-59-2
• Molecular Formula: C₆H₁₀N₃O₂*Cl
• Molecular Weight: 191.62
• EINECS: 229-266-8
• Product Categories: Histidine [His, H]
• Mol File: 6459-59-2.mol

Chemical Properties

• Melting Point: 233°C
• Boiling Point: 458.9 °C at 760 mmHg
• Flash Point: 231.3 °C
• Appearance: White/Crystalline Powder
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: DL-HISTIDINE MONOHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-HISTIDINE MONOHYDROCHLORIDE(6459-59-2)
• EPA Substance Registry System: DL-HISTIDINE MONOHYDROCHLORIDE(6459-59-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 22-26-36/37
• Hazardous Substances Data: 6459-59-2(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

InChI:InChI=1/C6H9N3O2.ClH/c7-5(6(10)11)1-4-2-8-3-9-4;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H/t5-;/m0./s1

Upstream product

• 645-35-2 L-histidine monohydrochloride 

Downstream Products

• 123760-89-4 DL-2-(4-chlorobenzyl)amino-3-(4-imidazolyl)propionic acid  
• 645-35-2 L-histidine monohydrochloride 
• 6341-24-8 D-histidine monohydrochloride 
• 18502-05-1 4-cyanomethylimidazole 
• 1048031-77-1 C₁₃H₁₂FN₃O₂ 
• 1620842-13-8 4⁽⁵⁾-(o-fluorophenylmethyl)-DL-histidine 
• 782441-07-0 C₁₃H₁₂FN₃O₂ 
• 771467-03-9 4⁽⁵⁾-(p-fluorophenylmethyl)-DL-histidine 

Relevant articles and documents

Method for the Racemization of Optically Active Amino Acids

A practical method for the racemization of optically active amino acids has been developed.A wide variety of optically active α-amino acids, including neutral amino acids, acidic amino acids, basic amino acids, and imino acids, could be racemized by heating in a medium of acetic acid at 80-100 deg C for 1 h in the presence of 0.05 molar equiv of an aliphatic or an aromatic aldehyde.The factors influencing the racemization were investigated.Phenylglycine, (p-hydroxyphenyl)glycine, and serine could be racemized without complete dissolution of the optically active isomers.Thus, isolation of the racemic modification was easily achieved by simple filtration of the racemic modification suspended in the reaction mixture.The mechanism of the racemization is discussed.