66727-64-8

Basic information

• Product Name: ASISCHEM W99822
• Synonyms: ASISCHEM W99822;TIMTEC-BB SBB010762;1-ETHYL-2-METHYL-1H-INDOLE-3-CARBALDEHYDE;1-ETHYL-2-METHYL-1H-INDOLE-3-CARBOXALDEHYDE;1H-INDOLE-3-CARBOXALDEHYDE, 1-ETHYL-2-METHYL-;1-ethyl-2-methyl-3-indolecarboxaldehyde;1-ethyl-2-methyl-indole-3-carbaldehyde;1-ethyl-2-methylindole-3-carbaldehyde
• CAS NO: 66727-64-8
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.241
• Mol File: 66727-64-8.mol

Chemical Properties

• Boiling Point: 343.9°C at 760 mmHg
• Flash Point: 161.8°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 6.82E-05mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: ASISCHEM W99822(CAS DataBase Reference)
• NIST Chemistry Reference: ASISCHEM W99822(66727-64-8)
• EPA Substance Registry System: ASISCHEM W99822(66727-64-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 66727-64-8(Hazardous Substances Data)

Usage

Uses

Used in the Food Industry:
ASISCHEM W99822 is used as a flavoring agent for enhancing the taste and aroma of various food products.
Used in Pharmaceutical Industry:
ASISCHEM W99822 is used as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new medications.
Used in Fragrance Industry:
ASISCHEM W99822 is used in the production of fragrances, adding unique scents to perfumes, cosmetics, and other scented products.
Used in Dye and Pigment Industry:
ASISCHEM W99822 is utilized in the manufacturing of dyes and pigments, providing vibrant colors for textiles, paints, and other applications.
Used in Medicinal Applications:
ASISCHEM W99822 is used for its anti-inflammatory and antioxidant properties, offering potential health benefits in the treatment of various conditions.
Used in Cosmetic Industry:
ASISCHEM W99822 is used in the production of sunscreen and other cosmetic products due to its ability to absorb UVB radiation, providing protection against harmful sun exposure.

InChI:InChI=1/C12H13NO/c1-3-13-9(2)11(8-14)10-6-4-5-7-12(10)13/h4-8H,3H2,1-2H3

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 40876-94-6 1-ethyl-2-methylindole 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 917207-79-5 1-ethyl-2-methyl-1H-indole-3-carbonitrile 

Relevant articles and documents

Selective nickel-catalyzed dehydrogenative-decarboxylative formylation of indoles with glyoxylic acid

Herein we present a new strategy for the dehydrogenative-decarboxylative coupling of indoles with glyoxylic acid. A broad range of indoles were transformed into the corresponding 3-formylindoles in moderate to good yields and excellent functional group tolerance. Notably, no N-formylation product was detected under our conditions.

Cu(ii)-catalyzed C-H (SP3) oxidation and C-N cleavage: Base-switched methylenation and formylation using tetramethylethylenediamine as a carbon source

Base-switched methylenation and formylation using tetramethylethylenediamine (TMEDA) as a carbon source have been achieved under mild conditions, catalyzed by CuCl2, with atmospheric oxygen as oxidant. Bisindolylmethanes, diphenylmethanes and 3-formylindoles were synthesized with excellent regioselectivity and good yield.

Novel compounds, processes and marking systems

Mono and bis substituted (arylsulfonyl)alkanes useful as color formers, particularly in carbonless duplicating and thermal marking systems, are prepared by the interaction of the appropriate aldehyde or dialdehyde with the appropriate aryl or heterocyclic moiety and the appropriate phenylsulfinic acid in the presence of a catalyst.