68327-30-0

Basic information

• Product Name: diethyl 2-oxocyclohexane-1,3-dicarboxylate
• CAS NO: 68327-30-0
• Molecular Formula: C₁₂H₁₈O₅
• Molecular Weight: 242.2683
• Mol File: 68327-30-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 325.9°C at 760 mmHg
• Flash Point: 141°C
• Density: 1.147g/cm³
• Vapor Pressure: 0.000223mmHg at 25°C
• Refractive Index: 1.47
• CAS DataBase Reference: diethyl 2-oxocyclohexane-1,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-oxocyclohexane-1,3-dicarboxylate(68327-30-0)
• EPA Substance Registry System: diethyl 2-oxocyclohexane-1,3-dicarboxylate(68327-30-0)

Safety Data

• Hazardous Substances Data: 68327-30-0(Hazardous Substances Data)

Upstream product

• 3779-30-4 pentane-1,1,5,5-tetracarboxylic acid tetraethyl ester 
• 141-52-6 sodium ethanolate 
• 64-17-5 ethanol 
• 22775-31-1 2-oxo-cyclohexane-1,3-dicarboxylic acid 
• 109-64-8 1,3-dibromo-propane 
• 105-50-0 diethyl 1,3-acetonedicarboxylate 
• 2414-98-4 magnesium ethylate 
• 53007-36-6 1,1,5-pentanetricarboxylic acid triethyl ester 

Downstream Products

• 108-94-1 cyclohexanone 
• 852050-65-8 diethyl 3-((4-methoxyphenyl)methyl)-9-oxo-3-azabicyclo[3.3.1]nonane-1,5-dicarboxylate 
• 101289-05-8 3-oxo-2-phenyl-2,3,4,5,6,7-hexahydro-1H-indazole-7-carboxylic acid ethyl ester 

Relevant articles and documents

A class of chiral beta-hydroxyamide compounds, preparation method and applications thereof,

The invention discloses a chiral beta-hydroxyamide compound and a preparation method thereof, wherein the compound is represented by a formula I. According to the invention, the raw material for preparing a non-natural chiral amino acid compound is obtained by carrying out catalytic hydrolysis on a prochiral diamide compound II with different substituents by using a Rhodococcus erythropolis AJ270microbial system, wherein the use amount of the Rhodococcus erythropolis can be adjusted according to the use amount of a substrate, the reaction solvent is a common buffer solution with the pH valueof 6.0-8.0, the temperature is 20-37 DEG C, the reaction time is 3-120 h, and the Rhodococcus erythropolis microbial catalytic system can be cultured through fermentation and conveniently stored; andwith the application of the biotransformation to prepare chiral monoamide carboxylic acid and dicarboxylic acid, the characteristics of simplicity and convenience in operation, high reaction efficiency, mild reaction conditions, high enantioselectivity, easiness in product separation and high product purity are achieved, and the application prospect is god.

Alkylation of Diethyl 3-Oxoglutarate with α,ω-Dibromoalkanes

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