68471-58-9

Basic information

• Product Name: 3,4-Dihydro-1(2H)-pyridinecarboxylic Acid Phenylmethyl Ester
• Synonyms: 3,4-Dihydro-1(2H)-pyridinecarboxylic Acid Phenylmethyl Ester;N-Benzyloxycarbonyl-1,2,3,4-tetrahydropyridine;3,4-Dihydro-2H-pyridine-1-carboxylic acid benzyl ester;N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine 97%;1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-, phenylmethyl ester;Benzyl 3,4-dihydropyridine-1(2H)-carboxylate;1-Z-3,4-Dihydro-2H-Pyridine
• CAS NO: 68471-58-9
• Molecular Formula: C₁₃H₁₅NO₂
• Molecular Weight: 217.26
• Product Categories: Aromatics Compounds;Aromatics;Heterocycles
• Mol File: 68471-58-9.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 347.7±35.0 °C(Predicted)
• Flash Point: >110℃
• Appearance: /
• Density: 1.123 g/mL at 25 °C
• Refractive Index: n20/D1.552
• PKA: -0.72±0.20(Predicted)
• CAS DataBase Reference: 3,4-Dihydro-1(2H)-pyridinecarboxylic Acid Phenylmethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-1(2H)-pyridinecarboxylic Acid Phenylmethyl Ester(68471-58-9)
• EPA Substance Registry System: 3,4-Dihydro-1(2H)-pyridinecarboxylic Acid Phenylmethyl Ester(68471-58-9)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2810 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 68471-58-9(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Oil

Upstream product

• 3742-91-4 N-(benzyloxycarbonyl)piperidine 
• 2508-29-4 5-hydroxypentylamine 
• 501-53-1 benzyl chloroformate 
• 522-33-8 Tripiperidin 
• 69622-67-9 benzyl 2-hydroxypiperidine-1-carboxylate 
• 185847-84-1 benzyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate 
• 79328-85-1 N-benzyloxycarbonyl-1,2-dihydropyridine 
• 53708-19-3 4-isopropoxypyridine 
• 1468-47-9 5,5-diethoxy-valeronitrile 
• 21938-23-8 5-Aminopentanal Diethyl Acetal 
• 106412-35-5 N-benzyloxycarbonyl-2-piperidone 
• 210298-83-2 6-trifluoroomethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 185847-90-9 6-(2-Oxo-ethyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 185847-86-3 6-(3-Oxo-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 185847-88-5 6-But-3-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 185847-89-6 6-Pent-3-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 185847-87-4 6-(4,4-Dibromo-but-3-enyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 1246190-40-8 2-benzyl 7-ethyl 2-azabicyclo[4.1.0]heptane-2,7-dicarboxylate 

Relevant articles and documents

A lactam-derived vinyl boronate as a stable and crystalline reagent for the synthesis of 2-substituted piperidines by Pd-catalyzed coupling reactions

A δ-valerolactam-derived vinyl triflate has been converted into the corresponding vinyl boronate by Pd-catalyzed coupling with bis(pinacolato) diboron, which results in an umpolung. This boronate efficiently couples under Pd catalysis with aryl and hetero

Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates

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A process for the preparation and synthetic ChondriamideA and ChondriamideC method (by machine translation)

The invention provides a process for the preparation of synthetic Chondriamide A and Chondriamide C and method, wherein the invention provides a process for the preparation, including: formula (I) compounds of structure, palladium catalyst, phosphorus ligand, alkali and organic solvent at room temperature the illumination reaction, formula (II) structure obtained olefin; wherein through the selection of a particular phosphorus ligand; make the method of the invention can be under the photocatalysis, room temperature to realize high-efficient catalytic conversion, and the mild reaction conditions, simple operation, in line with the development of green environment-friendly chemical requirements, and the range of choice of substrate and functional group compatibility has more universal, and has outstanding chemical selectivity; and the method can be successfully applied to complex molecular introducing carbon-carbon double bond to the programme, to optimize a part of the drug molecular synthesis strategy, improve the synthesis efficiency, reduce the cost, with industrial synthetic value and prospects. (by machine translation)