185847-89-6

Upstream product

• 185847-86-3 6-(3-Oxo-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 185847-85-2 benzyl 2-allyl-5,6-dihydropyridine-1(2H)-carboxylate 
• 185847-84-1 benzyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate 
• 68471-58-9 1-(benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine 
• 501-53-1 benzyl chloroformate 
• 53708-19-3 4-isopropoxypyridine 
• 185847-87-4 6-(4,4-Dibromo-but-3-enyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

Exploitation of palladium-catalyzed reductive enyne cyclization in the synthesis of (-)-4a,5-dihydrostreptazolin

Hydroxyl-promoted reductive cyclization of enyne compounds catalyzed by Pd(OAc)2-BBEDA was explored and found to effect constructing the pyrindine framework with the alkylidene appendage. This methodology was applied to the stereoselective synthesis of (-)-4a,5-dihydrostreptazolin.