69355-99-3 Usage
Uses
Used in Pharmaceutical Industry:
N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine is used as a key intermediate in the synthesis of millepachine amino acid prodrugs for its enhanced solubility. This improved solubility contributes to the development of antitumor agents with better pharmacokinetic properties and therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 69355-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,5 and 5 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 69355-99:
(7*6)+(6*9)+(5*3)+(4*5)+(3*5)+(2*9)+(1*9)=173
173 % 10 = 3
So 69355-99-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO5/c1-11(21-10-12-8-6-5-7-9-12)13(14(18)19)17-15(20)22-16(2,3)4/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19)/t11-,13+/m0/s1
69355-99-3Relevant articles and documents
Dehydrooligopeptides. XVII. Practical syntheses of all of the diastereomers of N,N-protected 2,3-diaminobutanoic acids from L- and D-threonine derivatives
Nakamura,Hirai,Tamotsu,Yonezawa,Shin
, p. 1369 - 1377 (2007/10/02)
Syntheses of all of the dioctereomers of 2,3-diaminobutanoic acids, found in some pedtide antibiotics and toxins, were accomplished. The four isomers were derived mainly through two pathways including S(N)2 inversions of the β-substituent of L- or D-threonine derivatives. The various protecting groups and effective nucleophiles for the S(N)2 inversion were examined.
