6947-94-0

Basic information

• Product Name: 2-METHYL-3-FUROIC ACID
• Synonyms: AKOS BBS-00000136;2-METHYL-3-FURANCARBOXYLIC ACID;2-METHYL-3-FUROIC ACID;2-METHYLFURAN-3-CARBOXYLIC ACID;IFLAB-BB F1901-0076;TIMTEC-BB SBB004258;2-Methyl-3-furoicacid,98%;2-Methyl-3-furoic acid, GC 98%
• CAS NO: 6947-94-0
• Molecular Formula: C₆H₆O₃
• Molecular Weight: 126.11
• EINECS: -0
• Product Categories: Building Blocks;C4 to C7;Chemical Synthesis;Furans;Heterocyclic Building Blocks
• Mol File: 6947-94-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 102-105 °C
• Boiling Point: 174.21°C (rough estimate)
• Flash Point: 93.8 °C
• Appearance: light brown crystalline needles and chunks
• Density: 1.2048 (rough estimate)
• Vapor Pressure: 0.0347mmHg at 25°C
• Refractive Index: 1.4189 (estimate)
• Storage Temp.: 2-8°C
• PKA: 4.37±0.20(Predicted)
• BRN: 112229
• CAS DataBase Reference: 2-METHYL-3-FUROIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-3-FUROIC ACID(6947-94-0)
• EPA Substance Registry System: 2-METHYL-3-FUROIC ACID(6947-94-0)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 45-36/37/39-26
• RIDADR: UN 3261 8/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 6947-94-0(Hazardous Substances Data)

Usage

Chemical Properties

light brown crystalline needles and chunks

InChI:InChI=1/C6H6O3/c1-4-5(6(7)8)2-3-9-4/h2-3H,1H3,(H,7,8)/p-1

Upstream product

• 28921-35-9 2-methyl-3-ethoxycarbonyl-furan 
• 17276-95-8 2-methyl-furan-3,5-dicarboxylic acid 
• 130446-63-8 4-acetyl-5-methyl-furan-2-carboxylic acid 
• 6141-58-8 methyl 2-methyl-3-furancarboxylate 
• 141764-76-3 2-Methyl-5-phenylsulfanyl-4,5-dihydro-furan-3-carboxylic acid ethyl ester 
• 488-93-7 3-Furoic acid 
• 208777-57-5 2-methoxymethyl-3-furoic acid 
• 90812-71-8 lithium 2-lithiofuran-3-carboxylate 
• 74-88-4 methyl iodide 
• 196601-49-7 2-(carboxymethyl)furan-3-carboxylic acid 
• 141-97-9 ethyl acetoacetate 
• 141-46-8 Glycolaldehyde 
• 852238-06-3 ethyl 2-(2-ethoxy-2-oxoethyl)furan-3-carboxylate 
• 29172-08-5 ethyl 4-acetyl-5-methylfuran-2-carboxylate 

Downstream Products

• 5555-00-0 2-methylfuran-3-carbonyl chloride 
• 447449-10-7 C₁₂H₉ClFNO₂ 
• 1282102-35-5 6-(2-methylfuran-3-yl)-3-(pyridin-4-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1572514-37-4 C₁₆H₁₉FN₂O₄S 
• 1036113-64-0 3'-isopropyl-2-methylfuran-3-carboxylic acid anilide 

Relevant articles and documents

Design, synthesis and antifungal activity of novel fenfuram-diarylamine hybrids

Ten novel fenfuram-diarylamine hybrids were designed and synthesized. And their antifungal activities against four phytopathogenic fungi have been evaluated in vitro and most of the compounds demonstrated a significant antifungal activities against Rhizoctonia solani and Sclerotinia sclerotiorum. Compound 5e exhibited the most potent antifungal activity against R. solani with an EC50value of 0.037 mg/L, far superior to the commercially available fungicide boscalid (EC50= 1.71 mg/L) and lead fungicide fenfuram (EC50= 6.18 mg/L). Furthermore, scanning electron microscopy images showed that the mycelia on treated media grew abnormally with tenuous, wizened and overlapping colonies compared to the negative control. Molecular docking studies revealed that compound 5e featured a higher affinity for succinate dehydrogenase (SDH) than fenfuram. Furthermore, it was shown that the 3-chlorophenyl group in compound 5e formed a CH-π interaction with B/Trp-206 and a Cl-π interaction with D/Tyr-128, rendering compound 5e more active than fenfuram against SDH.

Anti-viral aromatic hydrazones

Compounds of the formula STR1 wherein Q is a hydrazone derivative; R1 is hydrogen, halogen, alkyl or alkoxy; R2 is hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkynyloxy, halomethyl, trifluoromethoxy, alkylthio, nitro or cyano; and R

The Birch Reduction of Heterocyclic Compounds. III. [1] Birch Reduction-Elimination Reaction of 2- and 3-Furancarboxylic Acid Derivatives

The Birch reduction of 2-(1-alkoxyalkyl)furan-3-carboxylic acids la-f gave 2-alkyl-3-furancarboxylic acids 2a-f with loss of the alkoxyl group in excellent isolated yields.