71810-97-4

Basic information

• Product Name: (2R)-2-Aminopropanamide hydrochloride
• Synonyms: (2R)-2-AMINOPROPANAMIDE HYDROCHLORIDE;H-D-ALA-NH2 HCL;D-ALANINE AMIDE HYDROCHLORIDE;D-ALANINAMIDE HYDROCHLORIDE;D-ALANINE-NH2 HCL;D-Ala-NH2 HCl;D-AlaninamideHCl;H-D-Ala-NH2HCl(D-AlanineamideHCl)
• CAS NO: 71810-97-4
• Molecular Formula: C₃H₈N₂O*ClH
• Molecular Weight: 124.57
• EINECS: 1533716-785-6
• Product Categories: Amino Acids;Alanine [Ala, A]
• Mol File: 71810-97-4.mol

Chemical Properties

• Melting Point: 169 °C
• Boiling Point: 247.4 °C at 760 mmHg
• Flash Point: 103.4 °C
• Appearance: White/Powder
• Vapor Pressure: 0.0257mmHg at 25°C
• Storage Temp.: 2-8°C
• Water Solubility: Soluble in 1% acetic acid and water.
• CAS DataBase Reference: (2R)-2-Aminopropanamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-Aminopropanamide hydrochloride(71810-97-4)
• EPA Substance Registry System: (2R)-2-Aminopropanamide hydrochloride(71810-97-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 71810-97-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(2R)-2-Aminopropanamide hydrochloride is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows for the formation of new bonds and reactions, facilitating the synthesis of complex organic molecules.
Used in Pharmaceuticals:
In the pharmaceutical industry, (2R)-2-Aminopropanamide hydrochloride is utilized as an important building block in the development of new drugs. Its versatile chemical properties enable it to be incorporated into the molecular structures of potential therapeutic agents, contributing to the advancement of medicinal chemistry.
Used in Agrochemicals:
(2R)-2-Aminopropanamide hydrochloride also finds application in the agrochemical sector, where it is employed as a vital component in the synthesis of various agrochemical products. Its role in this industry is crucial for the development of effective and innovative solutions for agricultural challenges.

InChI:InChI=1/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/m1./s1

Upstream product

• 1336-21-6 ammonium hydroxide 
• 3744-87-4 Boc-(R)-Ala 
• 541-41-3 chloroformic acid ethyl ester 
• 302-72-7 rac-Ala-OH 
• 78981-25-6 N-(tert-butoxycarbonyl)-D-alanine amide 

Downstream Products

• 145126-21-2 Moz-Phe-D-Ala-NH₂ 
• 123253-85-0 N-(4-Methoxycarbonyl)-O-benzylaspargyl-D-alanine amide 
• 688755-97-7 (S)-N-((R)-1-carbamoyl-ethyI)-2-[(R)-5-(4-cyano-benzyl)-7-(3,5-dichloro-phenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide 
• 374756-15-7 Z-L-alanyl-D-alanamide 
• 338-69-2 D-Alanine 

Relevant articles and documents

Biosynthesis method and application of N-methyl-o-carborane-L-propionamide

The invention discloses a biosynthesis method of N-methyl-o-carborane-L-propionamide, which comprises the following steps: 1, synthesizing L-propionamide by using D,L-alanine and ammonia water as raw materials and laccase as a catalyst, filtering the reaction product to remove the laccase, and introducing hydrogen chloride gas to generate L-propionamide hydrochloride; 2, in an organic solvent or ionic liquid, reacting with 1-bromomethyl-o-carborane under an alkaline condition to obtain the corresponding o-carborane derivative. According to the invention, through the degradation characteristics of laccase on amines and alcohols, it is accidentally found that laccase has the function of synthesizing the L-propylamine amide, and has the characteristics of high yield, safety, no pollution and the like. Therefore, by chemically synthesizing and modifying o-carborane and a relatively hydrophilic group L-propionamide, the purpose of increasing the polarity and cell affinity of the compound is achieved, so that the technical effect of targeted enrichment and high concentration of boron ions in tumor cells is achieved.

BICYCLIC COMPOUNDS

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.

HIV PROTEASE INHIBITORS

Peptide mimics, having a constrained peptide backbone conformation, are HIV protease inhibitors. A compound of this invention is, for example, 3-Benzyl-5(alaninyl-1-aminoethyl)-2,3,6,7-tetrahydro-N-azepinyl-2-propionyl-valinyl-valinyl methyl ester.