71868-10-5Relevant articles and documents
Preparation method of 2-methyl-1-(4-substituted phenyl)-2-morpholinyl-1-acetone
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, (2021/03/30)
The invention relates to a preparation method of 2-methyl-1-(4-substituted phenyl)-2-morpholinyl-1-acetone. The preparation method comprises two steps of epoxidation reaction and morpholine substitution reaction, wherein in the morpholine substitution reaction, a proper amount of an auxiliary agent is added, and the auxiliary agent is selected from at least one of water, a strong-acid weak-alkalisaline solution and a strong-alkali weak-acid saline solution, so that the ring opening rate and the ring opening selectivity in the morpholine substitution reaction process can be obviously improved,and the overall reaction rate and yield are further improved, according to the method, the problem that subsequent catalysts are difficult to filter, recycle and purify due to the fact that catalystssuch as carclazyte need to be added in the traditional process is solved, the high-purity 2-methyl-1-(4-substituted phenyl)-2-morpholinyl-1-acetone can be obtained more easily, the process cost and the aftertreatment operation risk are reduced, and the economic benefit is improved.
PROCESS FOR THE PREPARATION OF ALPHA-FUNCTIONALIZED KETONES
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Page/Page column 49; 50; 51; 52, (2018/11/22)
The present invention refers to a process for the preparation of an α-functionalized ketone, an α-functionalized ketone obtained by said process, a photopolymerizable composition comprising the α-functionalized ketone and at least one photopolymerizable unsaturated compound, a method of preparing an article, an article obtained by said method, as well as the use of the α-functionalized ketone or the photopolymerizable composition as photoinitiator.
Synthetic method of free-radical photoinitiator
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Paragraph 0053; 0054; 0063; 0064; 0075; 0102, (2018/07/30)
The invention discloses a synthetic method of a free-radical photoinitiator. The synthetic method is characterized by comprising the following steps: (1) under the action of aluminium trichloride, methyl phenyl sulfide is adopted as a raw material and generates Friedel-Crafts acylation reaction with 2-chloroisobutyryl chloride to prepare an intermediate A with a structure shown in a formula (I); (2) under the action of alkaline, the intermediate A carries out ring-closure reaction to prepare an intermediate B with a structure shown in a formula (II); (3) the intermediate B and morpholine carryout ring-opening reaction to obtain a target product with a structure shown in a formula (III), namely the free-radical photoinitiator. The synthetic method disclosed by the invention has the beneficial effects that the photoinitiator is synthesized by the steps of adopting the 2-chloroisobutyryl chloride and methyl phenyl sulfide to carry out Friedel-Crafts acylation reaction, then carrying outcyclization and ring opening and the like, the obtained product contains fewer impurities, the yield is high, the process route is convenient in operation, and generates less three wastes (waste water, waste solid and waste air) so as to be more environment-friendly.