1569-69-3 Usage
Chemical Properties
CLEAR LIQUID
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 6057, 1994 DOI: 10.1016/0040-4039(94)88074-3
General Description
A colorless liquid with a strong disagreeable odor. Insoluble in water and less dense than water. Vapors heavier than air. Flash point near 50°F.
Air & Water Reactions
Highly flammable. Insoluble in water.
Reactivity Profile
Cyclohexyl mercaptan is incompatible with the following: Oxidizers, reducing agents, strong acids, alkali metals .
Health Hazard
May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
Safety Profile
Poison by intravenous
route. Moderately toxic by ingestion,
subcutaneous, and intramuscular routes.
Mildly toxic by skin contact. Human
systemic effects by inhalation: conjunctiva
irritation and changes in the olfactory and
respiratory systems. Has caused damage to
kidneys, liver, and blood vessels in
experimental animals. Experimental
reproductive effects. Human mutation data
reported. A severe eye irritant. Narcotic-like
action. Flammable when exposed to heat or flame; can react with oxiduing materials.
Iptes on contact with chromium trioxide.
Violent reaction with HNO3. Incompatible
with oxidants. To fight fire, use alcohol
foam, foam, CO2, dry chemical. When
heated to decomposition it emits acrid
smoke and fumes. See also ALCOHOLS.
Check Digit Verification of cas no
The CAS Registry Mumber 1569-69-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,6 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1569-69:
(6*1)+(5*5)+(4*6)+(3*9)+(2*6)+(1*9)=103
103 % 10 = 3
So 1569-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H12S/c7-6-4-2-1-3-5-6/h6-7H,1-5H2
1569-69-3Relevant articles and documents
Thiolation of cycloalkenes C5, C6 by redox-activation of hydrogen sulfide
Shinkar, Elena V.,Kudryavtsev, Daniil A.,Pashchenko, Konstantin P.,Berberova, Nadezhda T.,Okhlobystina, Alexandra V.
, p. 180 - 182 (2017)
Direct and indirect redox-activation of H2S in the presence of cyclopentene or cyclohexene in MeCN at 25?°C affords the corresponding cycloalkanethiols.
The benzyl can be selectively removed by visible light or near visible light. Method for protecting allyl and propargyl group
-
Paragraph 0031, (2021/10/16)
The invention provides a method for selectively removing benzyl, allyl and propargyl protecting groups by visible light or near visible light, namely a substrate containing benzyl, allyl or propargyl protecting groups. The method has the advantages of simple operation, safe and clean visible light or near visible light as excitation conditions, cheap and easily available reagents, high reaction yield, high reaction chemistry and regional selectivity, and is suitable for selective removal of benzyl, allyl and propargyl protecting groups in various substrates.
Insight into the Mechanism of Reversible Ring-Opening of 1,3-Benzoxazine with Thiols
Urbaniak, Tobias,Soto, Marc,Liebeke, Manuel,Koschek, Katharina
, p. 4050 - 4055 (2017/04/27)
The reversible ring-opening addition and fragmentation reaction of p-cresol-based N-phenylbenzoxazine with aliphatic and aromatic thiols was investigated in solvent-mediated and solvent-free reactions. Independently of the used thiol, N-phenylbenzoxazine and the thiols reacted to equilibrium with comparable amounts of reactants and products in aprotic solvent, whereas in protic solvent almost full conversions were reached. In contrast, thiol reactivity was a crucial factor in solvent-free reactions yielding fast and complete conversions for a more acidic thiol and balanced equilibrium concentrations in case of thiols with high pKa values. The strong influence of thiols with low pKa values emphasizes the relevance of the protonation step in the ring-opening reactions of 1,3-benzoxazines with thiols in absence of solvents where acidity predominates nucleophilicity. The reverse reactions, namely adduct dissociation and benzoxazine recovery, were successfully conducted at elevated temperatures and reduced pressure facilitated by the removal of the formed thiols yielding up to 95% recovered 1,3-benzoxazine. These results provide deeper understanding of the reversible ring-opening reaction mechanism of 1,3-benzoxazine with thiols.