736928-22-6

Basic information

• Product Name: 2-Bromo-9-phenyl-9H-fluoren-9-ol
• Synonyms: 9H-Fluoren-9-ol,2-bromo-9-phenyl-;2-bromo-9-phenyl-9H-fluoren-9-ol;2-Bromo-9-phenyl-9H-;2-DroMo-9-phenyl-9H-fluoren-9-OL;2-Bromo-9-phenyl-9-fluorenol
• CAS NO: 736928-22-6
• Molecular Formula: C₁₉H₁₃BrO
• Molecular Weight: 337.21
• EINECS: 1312995-182-4
• Product Categories: Electronic Chemicals
• Mol File: 736928-22-6.mol

Chemical Properties

• Boiling Point: 482.7±33.0 °C(Predicted)
• Appearance: /
• Density: 1.504±0.06 g/cm3(Predicted)
• Refractive Index: 1.708
• PKA: 12.42±0.20(Predicted)
• CAS DataBase Reference: 2-Bromo-9-phenyl-9H-fluoren-9-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-9-phenyl-9H-fluoren-9-ol(736928-22-6)
• EPA Substance Registry System: 2-Bromo-9-phenyl-9H-fluoren-9-ol(736928-22-6)

Safety Data

• Hazardous Substances Data: 736928-22-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Bromo-9-phenyl-9H-fluoren-9-ol is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for versatile functionalization and modification, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Bromo-9-phenyl-9H-fluoren-9-ol is employed as a starting material for the development of new drugs. Its potential biological activities, such as anticancer and antimicrobial properties, have attracted significant attention from researchers. 2-Bromo-9-phenyl-9H-fluoren-9-ol's ability to modulate various signaling pathways and target specific enzymes makes it a promising candidate for the treatment of various diseases.
Used in Material Development:
2-Bromo-9-phenyl-9H-fluoren-9-ol has been investigated for its potential use in the development of new materials. Its unique structure and properties make it suitable for the creation of advanced materials with specific characteristics, such as high thermal stability, optical properties, or electronic properties. These materials can be utilized in various applications, including sensors, electronic devices, and coatings.
Used in Anticancer Applications:
2-Bromo-9-phenyl-9H-fluoren-9-ol is used as an anticancer agent, exhibiting potential inhibitory effects on the growth and progression of various types of cancer cells. Its ability to modulate oncological signaling pathways and target specific proteins involved in cancer development makes it a promising candidate for cancer therapy. Further research is needed to optimize its efficacy and minimize side effects.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 2-Bromo-9-phenyl-9H-fluoren-9-ol is employed as an antimicrobial agent. Its potential to inhibit the growth of various microorganisms, including bacteria and fungi, has been studied. 2-Bromo-9-phenyl-9H-fluoren-9-ol's unique structure and properties allow it to target specific cellular processes, making it a valuable tool in the development of new antimicrobial drugs to combat drug-resistant infections.

InChI:InChI=1/C19H13BrO/c20-14-10-11-16-15-8-4-5-9-17(15)19(21,18(16)12-14)13-6-2-1-3-7-13/h1-12,21H

Upstream product

• 3096-56-8 2-bromofluoren-9-one 
• 100-59-4 phenylmagnesium chloride 
• 108-86-1 bromobenzene 
• 100-58-3 phenylmagnesium bromide 
• 486-25-9 9-fluorenone 
• 4269-17-4 4-bromo-9H-fluorene-9-one 

Downstream Products

• 474918-32-6 2-bromo-9,9-diphenyl-9H-fluorene 
• 868549-06-8 2-bromo-9-(4-methylphenyl)-9-phenyl-9H-fluorene 
• 1158844-76-8 C₃₁H₂₂ 
• 1158844-77-9 C₃₁H₂₀Br₂ 
• 1158844-78-0 C₄₃H₄₄B₂O₄ 
• 1158844-79-1 C₃₂H₂₄ 
• 1158844-80-4 C₃₂H₂₂Br₂ 
• 1158844-81-5 C₄₄H₄₆B₂O₄ 
• 1158844-48-4 C₇₂H₄₈ 
• 1449686-80-9 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9-phenyl-fluoren-9-ol 

Relevant articles and documents

A novel host material with high thermal stability for green electrophosphorescent device

A new bipolar host material based on triphenylamine, fluorene and 1,2-diphenyl-1H-benzo[d]imidazole moieties, N,N-diphenyl-4-(9-phenyl-2-(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-9H-fluoren-9-yl)aniline (DPPBIPFA), was designed and synthesized. The as-synthesized material was well characterized by1H and13C NMR spectroscopy, high-resolution mass spectrometry and thermogravimetric analysis, respectively. The photophysical and electrochemical properties of the material were also studied. The material exhibited an excellent thermal stability (Td= 475 °C), electrochemical stability and high triplet energy (2.68 eV). A green phosphorescent organic light-emitting diode (PhOLED) device based on DPPBIPFA as the host material and Ir(ppy)3as the dopant was fabricated, which displayed favorable electrophosphorescent properties with a turn-on voltage of 3.75 V, a maximum brightness of 1685 cd/m2and a maximum current efficiency of 4.26 cd/A.

Preparation method 2 -amino -9-9 - diphenyl fluorene

The invention discloses a preparation method of 2 - amino -9 and 9 - diphenyl fluorene, which comprises the following steps: taking 9 - fluorenone as a raw material, and carrying out bromination reaction to obtain 2 - bromo -9 - fluorenone. 2 - Bromo -9 - fluorenone and bromobenzene formative reagent are reacted to obtain 2 - bromo -9 - phenyl -9 - hydroxyl - fluorene. 2 - Bromo -9 - phenyl -9 - hydroxy - fluorene was subjected to an alkylation reaction with benzene to give 2 - bromo -9, 9 - diphenylfluorene. 2 - Bromo -9, 9 - diphenylfluorene and cuprous oxide, palladium acetate (II) and N - methylpyrrolidinone were reacted in liquid ammonia to give 2 - amino -9, 9 - diphenylfluorene. The preparation method is used for preparing 2 - amino -9 and 9 - diphenylfluorene, the used preparation is easy to obtain, the technological process is simple, the product yield is high, the production cost is reduced, 2 - amino -9 and 9 - diphenyl fluorene are produced.

Cyclic tension organic material synthesis and preparation and application thereof

A cyclic tension organic material, characterized in that a cyclic molecule having a ring tension and a structural rigidity is constructed based on fluorene or fluorene, wherein n is a natural number of 1-10 and R is a natural number in the general formula

Ink Composition and Method for Manufacturing Organic Light Emitting Device

The present specification relates to an ink composition including: a compound represented by Formula 1; and a solvent represented by the Formula 2, and a method for manufacturing an organic light emitting device formed by using the ink composition.

Compound, Coating Composition Comprising Same, and Organic Light-Emitting Device

The present specification relates to a compound, a coating composition including the same, and an organic light emitting device.

Supramolecular Non-Helical One-Dimensional Channels and Microtubes Assembled from Enantiomers of Difluorenol

The design and assembly of photoelectro-active molecular channel structures is of great importance because of their advantages in charge mobility, photo-induced electron transfer, proton conduction, and exciton transport. Herein, we report the use of racemic 9,9′-diphenyl-[2,2′-bifluorene]-9,9′-diol (DPFOH) enantiomers to produce non-helical 1D channel structures. Although the individual molecule does not present any molecular symmetry, two pairs of racemic DPFOH enantiomers can form a C2-symmetric closed loop via the stereoscopic herringbone assembly. Thanks to the special symmetry derived from the enantiomer pairs, the multiple supramolecular interactions, and the padding from solvent molecules, this conventionally unstable topological structure is achieved. The etching of solvent in 1D channels leads to the formation of microtubes, which exhibit a significant lithium-ion conductivity of 1.77×10?4 S cm, indicating the potential research value of this novel 1D channel structure.

COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME

The present specification relates to a compound of Chemical Formula 1, a coating composition including the compound of Chemical Formula 1, an organic light emitting device using the same, and a method for manufacturing the same.

MANUFACTURING METHOD OF ORGANIC COMPOUND

A specification of the present invention provides a method for manufacturing an organic compound. The method comprising: a first step of making a compound represented by chemical formula 1 react with phenylmagnesium bromide; and a second step of making phenol react with a first product obtained through the first step. The present specification is intended to provide the method of manufacturing an organic compound capable of mass production without including a cryogenic process.COPYRIGHT KIPO 2020

MANUFACTURING METHOD OF ORGANIC COMPOUND

The present specification provides a method for manufacturing an organic compound, comprising: a first step of making a compound represented by chemical formula 1 react with phenylmagnesium bromide; and a second step of making phenol react with a first product obtained through the first step, wherein the second step includes a process of purifying a second product through a recrystallization process. The present specification is intended to provide the method of manufacturing an organic compound capable of mass production without including a cryogenic process.COPYRIGHT KIPO 2021

A Sc(OTf)3 catalyzed dehydrogenative reaction of electron-rich (hetero)aryl nucleophiles with 9-aryl-fluoren-9-ols

A highly efficient dehydrogenative reaction of a series of nucleophiles with 9-aryl-fluoren-9-ols has been realized by using only 2 mol% of Sc(OTf)3 as a catalyst. The corresponding indole-containing 9,9-diarylfluorenes were obtained in up to 99% yield as well as other electron-rich (hetero)arene adducts. The protocol exhibits high selectivity, mild reaction conditions and good substrate compatibility (32 examples). This protocol is further highlighted by its applications in the construction of potential electroluminescent materials.