74470-43-2 Usage
General Description
Methyl 5-(Methylthio)nicotinate is a chemical compound that is derived from the ester of nicotinic acid and methanol. It is a derivative of niacin, also known as vitamin B3, and is commonly used in pharmaceuticals and skincare products. Methyl 5-(Methylthio)nicotinate is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in topical treatments for skin conditions such as acne and eczema. Methyl 5-(Methylthio)nicotinate also has vasodilatory effects, meaning it can help improve blood flow and circulation when applied to the skin. Overall, this chemical has a range of potential health and skincare benefits, making it an important ingredient in many products.
Check Digit Verification of cas no
The CAS Registry Mumber 74470-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74470-43:
(7*7)+(6*4)+(5*4)+(4*7)+(3*0)+(2*4)+(1*3)=132
132 % 10 = 2
So 74470-43-2 is a valid CAS Registry Number.
74470-43-2Relevant articles and documents
SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES
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Paragraph 0251, (2021/11/20)
Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.
Nicotinyl aspartyl ketones as inhibitors of caspase-3
Isabel, Elise,Black, W. Cameron,Bayly, Christopher I.,Grimm, Erich L.,Janes, Marc K.,McKay, Daniel J.,Nicholson, Donald W.,Rasper, Dita M.,Renaud, Johanne,Roy, Sophie,Tam, John,Thornberry, Nancy A.,Vaillancourt, John P.,Xanthoudakis, Steven,Zamboni, Robert
, p. 2137 - 2140 (2007/10/03)
Caspase-3 is a cysteinyl protease that mediates apoptotic cell death. Its inhibition may have an important impact in the treatment of several degenerative diseases. Since P1 aspartic acid is a required element of recognition for this enzyme, a
