76470-34-3

Basic information

• Product Name: 5,6-Dimethoxynicotinic acid
• Synonyms: 5,6-Dimethoxynicotinic acid;3-Pyridinecarboxylic acid, 5,6-dimethoxy-
• CAS NO: 76470-34-3
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.16136
• Mol File: 76470-34-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 307.0±37.0 °C(Predicted)
• Appearance: /
• Density: 1.279±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.62±0.10(Predicted)
• CAS DataBase Reference: 5,6-Dimethoxynicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-Dimethoxynicotinic acid(76470-34-3)
• EPA Substance Registry System: 5,6-Dimethoxynicotinic acid(76470-34-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 76470-34-3(Hazardous Substances Data)

Usage

General Description

5,6-Dimethoxynicotinic acid is an organic chemical compound that belongs to the class of organic compounds known as dimethoxybenzenes, which are aromatic compounds containing two methoxy groups attached to a benzene ring. It is derived from nicotinic acid, also known as vitamin B3. While there's limited general or commercial information available about this particular compound, it is known that chemicals in this category are often used in the production of pharmaceuticals, agricultural chemicals and other industrial applications. Its molecular formula is C9H9NO4 and it has a molecular weight of 195.17 g/mol. This chemical is not typically found in natural environments but produced in laboratories. However, related compounds, such as vitamin B3, play an important role in human health and nutrition.

Upstream product

• 1112851-31-6 5,6-dimethoxypyridine-3-carbonitrile 
• 52605-98-8 5-bromo-2,3-dimethoxypyridine 
• 52605-97-7 2,3-dimethoxypyridine 

Relevant articles and documents

Nobiletin derivative or pharmaceutically acceptable salt thereof as well as preparation method and application thereof

The invention discloses a nobiletin derivative or a pharmaceutically acceptable salt thereof as well as a preparation method and application thereof. The nobiletin derivative has a structural formula(I) shown in the description, in the formula, R1, R2, R3 and R4 are respectively selected from hydrogen, halogen, hydroxyl, amino, C1-6 substituted or non-substituted alkoxy, a C1-6 substituted or non-substituted ester group, C1-6 substituted or non-substituted alkamino and a C1-6 substituted or non-substituted amide group; R5 is selected from a C3-9 substituted or non-substituted aromatic ring and a C3-9 substituted or non-substituted aromatic heterocyclic ring; and X is selected from O or NR6. The nobiletin derivative or the pharmaceutically acceptable salt thereof, which is disclosed by theinvention, is novel in structure, and in addition, the compound has an excellent inhibition function on P-gp, can be prepared into a P-gp inhibitor, is capable of treating and/or preventing related diseases caused by P-gp, particularly diseases related to tumor drug resistance, or can be mixed and used with other medicines and used as a drug resistance reversal agent, has a high reversion multiple, and is capable of remarkably improving medicine effects of medicines.