Welcome to LookChem.com Sign In|Join Free

CAS

  • or

52605-98-8

Post Buying Request

52605-98-8 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

52605-98-8 Usage

Description

5-Bromo-2,3-dimethoxypyridine is a pyridine derivative with the molecular formula C7H8BrNO2, featuring bromine, methoxy, and methyl groups. It is a valuable intermediate in the chemical industry, often used in organic synthesis and as a building block for the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and reactivity make it a promising candidate for the creation of various compounds.

Uses

Used in Organic Synthesis:
5-Bromo-2,3-dimethoxypyridine is used as a key intermediate in organic synthesis for the production of various compounds. Its reactivity and unique structure allow for the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
5-Bromo-2,3-dimethoxypyridine is used as a building block in the pharmaceutical industry for the development of new drugs. Its potential applications in medicinal chemistry and drug development are attributed to its ability to be modified to create compounds with specific biological activities.
Used in Agrochemical Industry:
5-Bromo-2,3-dimethoxypyridine is used as a precursor in the agrochemical industry for the synthesis of various agrochemicals. Its unique properties make it suitable for the development of new agrochemical products.
Used in Specialty Chemicals Industry:
5-Bromo-2,3-dimethoxypyridine is used as a component in the production of specialty chemicals. Its versatility and reactivity contribute to the development of specialized chemical products.
Safety Precautions:
It is important to handle 5-Bromo-2,3-dimethoxypyridine with care due to its potential hazards, including flammability and toxicity. Proper safety measures should be taken during its use and storage to minimize risks.

Check Digit Verification of cas no

The CAS Registry Mumber 52605-98-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,6,0 and 5 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52605-98:
(7*5)+(6*2)+(5*6)+(4*0)+(3*5)+(2*9)+(1*8)=118
118 % 10 = 8
So 52605-98-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8BrNO2/c1-10-6-3-5(8)4-9-7(6)11-2/h3-4H,1-2H3

52605-98-8 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Aldrich

  • (ADE000471)  5-Bromo-2,3-dimethoxypyridine  AldrichCPR

  • 52605-98-8

  • ADE000471-1G

  • 7,411.95CNY

  • Detail
  • Aldrich

  • (ADE000471)  5-Bromo-2,3-dimethoxypyridine  AldrichCPR

  • 52605-98-8

  • ADE000471-1G

  • 7,411.95CNY

  • Detail
  • Aldrich

  • (ADE000471)  5-Bromo-2,3-dimethoxypyridine  AldrichCPR

  • 52605-98-8

  • ADE000471-1G

  • 7,411.95CNY

  • Detail
  • Aldrich

  • (ADE000471)  5-Bromo-2,3-dimethoxypyridine  AldrichCPR

  • 52605-98-8

  • ADE000471-1G

  • 7,411.95CNY

  • Detail

52605-98-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2,3-dimethoxypyridine

1.2 Other means of identification

Product number -
Other names 5-bromo-2,3-dimethoxy-pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52605-98-8 SDS

52605-98-8Relevant articles and documents

Contorted Heteroannulated Tetraareno[a,d,j,m]coronenes

Yang, Xuan,Rominger, Frank,Mastalerz, Michael

supporting information, p. 14345 - 14352 (2021/09/13)

Fused polycyclic aromatic compounds are interesting materials for organic electronics applications. To fine-tune photophysical or electrochemical properties, either various substituents can be attached or heteroatoms (such as N or S) can be incorporated into the fused aromatic backbone. Coronenes and heterocoronenes are promising compounds in this respect. Up until now, the possibilities for varying the attached fused heteroaromatics at the coronene core were quite limited, and realizing both electron-withdrawing and -donating rings at the same time was very difficult. Here, a series of pyridine, anisole and thiophene annulated tetraareno[a,d,j,m]coronenes has been synthesized by a facile two-step route that is a combination of Suzuki-Miyaura cross-coupling and a following cyclization step, starting from three different diarenoperylene dibromides. The contorted molecular π-planes of the obtained cata-condensed tetraarenocoronenes were analyzed by single-crystal X-ray crystallography, and the photophysical and electrochemical properties were systematically investigated by UV/Vis spectroscopy and cyclovoltammetry.

D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF

-

Paragraph 0184, (2019/04/29)

The present invention relates to compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: each of A, B, C, D, and E, independently, is C, N, N—H, O, S, or absent is a single bond or a double bond; each of X, Y, and Z, independentl

Discovery of 5″-chloro-n-[(5,6-dimethoxypyridin-2- yl)methyl]-2,2':5',3″-Terpyridine-3'-carboxamide (mk-1064): A selective orexin 2 receptor antagonist (2-sora) for the treatment of insomnia

Roecker, Anthony J.,Mercer, Swati P.,Schreier, John D.,Cox, Christopher D.,Fraley, Mark E.,Steen, Justin T.,Lemaire, Wei,Bruno, Joseph G.,Harrell, C. Meacham,Garson, Susan L.,Gotter, Anthony L.,Fox, Steven V.,Stevens, Joanne,Tannenbaum, Pamela L.,Prueksaritanont, Thomayant,Cabalu, Tamara D.,Cui, Donghui,Stellabott, Joyce,Hartman, George D.,Young, Steven D.,Winrow, Christopher J.,Renger, John J.,Coleman, Paul J.

, p. 311 - 322 (2014/04/03)

The field of small-molecule orexin antagonist research has evolved rapidly in the last 15 years from the discovery of the orexin peptides to clinical proof-of-concept for the treatment of insomnia. Clinical programs have focused on the development of antagonists that reversibly block the action of endogenous peptides at both the orexin 1 and orexin 2 receptors (OX1R and OX2R), termed dual orexin receptor antagonists (DORAs), affording late-stage development candidates including Merck's suvorexant (new drug application filed 2012). Full characterization of the pharmacology associated with antagonism of either OX1R or OX2R alone has been hampered by the dearth of suitable subtype-selective, orally bioavailable ligands. Herein, we report the development of a selective orexin 2 antagonist (2-SORA) series to afford a potent, orally bioavailable 2-SORA ligand. Several challenging medicinal chemistry issues were identified and overcome during the development of these 2,5-disubstituted nicotinamides, including reversible CYP inhibition, physiochemical properties, P-glycoprotein efflux and bioactivation. This article highlights structural modifications the team utilized to drive compound design, as well as in vivo characterization of our 2-SORA clinical candidate, 5''-chloro-N- [(5,6-dimethoxypyridin-2-yl)methyl] -2,2':5',3''-terpyridine-3'-carboxamide (MK-1064), in mouse, rat, dog, and rhesus sleep models.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 52605-98-8