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CAS

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7656-14-6

D-Phenylalanine, N-(trifluoroacetyl)-, also known as trifluoroacetyl-D-phenylalanine, is a synthetic chemical compound that is a derivative of D-phenylalanine. It is commonly used as a reagent and building block in chemical synthesis, particularly in the production of peptides and pharmaceuticals. D-Phenylalanine, N-(trifluoroacetyl)is of interest to researchers and chemists due to its ability to modify the properties of peptides, such as enhancing their stability and bioavailability.

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  • (R)-N-(trifluoroacetyl)phenylalanine, (2~{R})-3-phenyl-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid

    Cas No: 7656-14-6

  • USD $ 9999.0-9999.0 / Gram

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  • 7656-14-6 Structure

  • Basic information

    1. Product Name: D-Phenylalanine, N-(trifluoroacetyl)-
    2. Synonyms:
    3. CAS NO:7656-14-6
    4. Molecular Formula: C11H10F3NO3
    5. Molecular Weight: 261.201
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 7656-14-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: D-Phenylalanine, N-(trifluoroacetyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: D-Phenylalanine, N-(trifluoroacetyl)-(7656-14-6)
    11. EPA Substance Registry System: D-Phenylalanine, N-(trifluoroacetyl)-(7656-14-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7656-14-6(Hazardous Substances Data)

7656-14-6 Usage

Uses

Used in Pharmaceutical Industry:
D-Phenylalanine, N-(trifluoroacetyl)is used as a reagent and building block for the synthesis of peptides and pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry and Drug Discovery:
Trifluoroacetyl-D-phenylalanine is used in the field of medicinal chemistry and drug discovery, where it aids in the study of peptide-protein interactions and the development of drug delivery systems.
Used in Chemical Synthesis:
D-Phenylalanine, N-(trifluoroacetyl)is used as a reagent in chemical synthesis, enabling the modification of peptide properties, such as enhancing their stability and bioavailability.

Check Digit Verification of cas no

The CAS Registry Mumber 7656-14-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,5 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7656-14:
(6*7)+(5*6)+(4*5)+(3*6)+(2*1)+(1*4)=116
116 % 10 = 6
So 7656-14-6 is a valid CAS Registry Number.

7656-14-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-3-phenyl-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid

1.2 Other means of identification

Product number -
Other names D-Phenylalanine,N-(trifluoroacetyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7656-14-6 SDS

7656-14-6Relevant articles and documents

TFA-protected α-amino acid N-hydroxysuccinimide ester: Application for inter- And intramolecular acylation

Tachrim, Zetryana Puteri,Oida, Kazuhiro,Ohashi, Fumina,Wakasa, Haruna,Ikemoto, Haruka,Kurokawa, Natsumi,Sakihama, Yasuko,Hashidoko, Yasuyuki,Suzuki, Takeyuki,Hashimoto, Makoto

, p. 877 - 893 (2019/04/26)

The utilization of N-trifluoroacetyl (TFA)-α-amino acid N-hydroxysuccinimide ester (OSu) derivatives, a promising acylating agent with high storage stability, is reported for Friedel-Crafts acylation into arenes and N-heterocycles. The reaction between TF

THE INCLUSION OF THE ENANTIOMERS OF N-TRIFLUOROACETYL-4-FLUOROPHENYLALANINE AND N-TRIFLUOROACETYLPHENYLALANINE BY CYCLOMALTOHEXAOSE: A 2H- AND 19F-N.M.R. STUDY

Smith, Nicholas J.,Spotswood, Thomas M.,Lincoln, Stephen F.

, p. 9 - 16 (2007/10/02)

19F-N.m.r. studies show that N-trifluoroacetyl-D- and -L-4-fluorophenylalanine and N-trifluoroacetyl-D- and -L-phenylalanine form 1:1 inclusion complexes with cyclomaltohexaose (α-cyclodextrin) characterised by stability constants of 11.44 +/- 1.13, 11.40 +/- 1.09, 6.15 +/- 0.59, and 6.37 +/- 0.81 M-1, respectively, in aqueous 0.1M NaCl at pH 6.5 and 25 deg C.Under similar conditions, the correlation time of N-trifluoroacetyl-phenylalanine changed from 65 +/- 4 ps in the free state to 320 +/- 40 ps in the complex, consistent with there being little freedom of movement of the guest in the inclusion complex.

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