383-63-1

Basic information

• Product Name: Ethyl trifluoroacetate
• Synonyms: aceticacid,trifluoro-,ethylester;CF3COOC2H5;Ethyl ester of Trifluoroacetic acid;Ethyl trifluoroethanoate;ethylperfluoroacetate;Trifluoressigsαureethylester;trifluoro-aceticaciethylester;ETHYL 2,2,2-TRIFLUOROACETATE
• CAS NO: 383-63-1
• Molecular Formula: C4H5F3O2
• Molecular Weight: 142.08
• EINECS: 206-851-6
• Product Categories: Fluoro-Aliphatics ;Acetics acid and esters;Organic Fluorides;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;organofluorine compounds;Building Blocks;C2 to C5;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks;Pharmaceutical intermediates
• Mol File: 383-63-1.mol

Chemical Properties

• Melting Point: -78 °C
• Boiling Point: 60-62 °C(lit.)
• Flash Point: 30 °F
• Appearance: Clear/Liquid
• Density: 1.194 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.307(lit.)
• Storage Temp.: 2-8°C
• Solubility: 4g/l
• Water Solubility: HYDROLYSIS
• Sensitive: Moisture Sensitive
• BRN: 1761411
• CAS DataBase Reference: Ethyl trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl trifluoroacetate(383-63-1)
• EPA Substance Registry System: Ethyl trifluoroacetate(383-63-1)

Safety Data

• Hazard Codes: F,Xn,C
• Statements: 11-22-37/38-41-34
• Safety Statements: 9-16-26-36/39-45-36/37/39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 1
• TSCA: T
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 383-63-1(Hazardous Substances Data)

Usage

Purification Methods

Fractionate it through a long Vigreux column (p 11). IR has max at 1800 (CO2) and 1000 (OCO) cm-1 [Fuson et al. J Chem Phys 20 1627 1952, Bergman J Org Chem 23 476 1958]. [Beilstein 2 IV 463.]

Uses

Widely used in the synthetic process of medicine, pesticides and organic intermediate.

Chemical Properties

Colorless to yellow liquid

Uses

Ethyl Trifluoroacetate is an intermediate used in the synthesis of various pharmaceutically active molecules and agricultural products. Ethyl Trifluoroacetate is also useful for the preparation of tri fluoroacylated compounds.

InChI:InChI=1/C4H5F3OS/c1-2-9-3(8)4(5,6)7/h2H2,1H3

Upstream product

• 76-05-1 Trifluoroacetic acid 

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