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7678-95-7

17α-Vinylestradiol is a synthetic derivative of the natural hormone estradiol, which is a primary female sex hormone. It is characterized by the presence of a vinyl group (C2H3) attached to the 17α position of the steroid nucleus. This modification enhances the compound's resistance to metabolic degradation, thereby increasing its potency and duration of action. 17α-Vinylestradiol is used in veterinary medicine, particularly in the treatment of hormonal imbalances and to control reproductive cycles in animals. It is important to note that the use of such synthetic hormones must be carefully regulated due to potential environmental and health implications, as they can have unintended effects on non-target species and ecosystems if not managed properly.

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  • 7678-95-7 Structure

  • Basic information

    1. Product Name: 17α-vinylestradiol
    2. Synonyms: 17α-vinylestradiol
    3. CAS NO:7678-95-7
    4. Molecular Formula:
    5. Molecular Weight: 298.425
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 7678-95-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 17α-vinylestradiol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 17α-vinylestradiol(7678-95-7)
    11. EPA Substance Registry System: 17α-vinylestradiol(7678-95-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7678-95-7(Hazardous Substances Data)

7678-95-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7678-95-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,7 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7678-95:
(6*7)+(5*6)+(4*7)+(3*8)+(2*9)+(1*5)=147
147 % 10 = 7
So 7678-95-7 is a valid CAS Registry Number.

7678-95-7Upstream product

7678-95-7Relevant articles and documents

Cathodic Birch Reduction of Methoxyaromatics and Steroids in Aqueous Solution

Kariv-Miller, Essie,Swenson, Karl E.,Zemach, Dvora

, p. 4210 - 4214 (1983)

The electroreduction of methoxybenzene, 1,2,3,4-tetrahydro-6-methoxynaphthalene, and several aromatic steroids using aqueous tetrabutylammonium hydroxide solutions is described.The reactions proceed in high yields, and the corresponding dihydro products are formed.Temperature and electrolyte concentration were found to have a strong effect on the reaction rate.A direct electron transfer to the aromatics is unlikely, and a possible reduction mechanism involving the intermediacy of tetrabutylammonium amalgam is proposed.

Solid phase synthesis of 17α-E/Z-(X-phenyl)-vinyl estradiols using the stille coupling reaction

Young Lee, Choon,Hanson, Robert N.

, p. 1623 - 1629 (2000)

As a continuation of our program to develop probes for the hormone binding domain (HBD) of the estrogen receptor (ER), we designed a series of novel 17α-E/Z-(X-phenyl)-vinyl estradiols. Based upon our experience with solution chemistry we applied solid phase synthesis using carboxylated resins to synthesize the new compounds. The Stille coupling reaction permitted the introduction of a variety of functional groups and positional isomers on the terminal phenyl group. Subsequent cleavage from the resin generated a series of novel estradiol derivatives. (C) 2000 Elsevier Science Ltd.

Organophosphorus Redox Systems

Kaim, Wolfgang,Lechner-Knoblauch, Ulrike,Haenel, Peter,Bock, Hans

, p. 4206 - 4208 (2007/10/02)

Redox systems involving R2P-, R2P(X)-, and R3P+ -substituted benzenes and biphenyls have been studied by cyclic voltammetry in dimethylformamide.The first one-electron reduction was found to be reversible in several instances, and stable radical anions, cations and uncharged radicals were detected by high-resolution electron spin resonance.The second reduction step was found to be irreversible in all cases investigated.The electrochemical and spectroscopic data illustrate the considerable difference in acceptor strength between R2P and R3P+ substituents; MO calculations of the radical species give a quantitative measure for this difference and for the overall substituent effects.A comparison is made between the organophosphorus redox systems presentented and the quinone/hydroquinone redox systems.

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