7697-25-8

Basic information

• Product Name: 2-CHLORO-4-METHYLBENZOIC ACID
• Synonyms: 4-Carboxy-3-chlorotoluene, 2-Chloro-p-toluic acid;Benzoicacid, 2-chloro-4-methyl-
• CAS NO: 7697-25-8
• Molecular Formula: C₈H₇ClO₂
• Molecular Weight: 170.5943
• Mol File: 7697-25-8.mol

Chemical Properties

• Melting Point: 195 °C
• Boiling Point: 303.5 °C at 760 mmHg
• Flash Point: 137.4 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 0.000407mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.19±0.25(Predicted)
• CAS DataBase Reference: 2-CHLORO-4-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-METHYLBENZOIC ACID(7697-25-8)
• EPA Substance Registry System: 2-CHLORO-4-METHYLBENZOIC ACID(7697-25-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 7697-25-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-methylbenzoic acid serves as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-4-methylbenzoic acid is utilized as an intermediate in the production of agrochemicals. Its involvement in the synthesis of these chemicals aids in the development of effective solutions for agricultural applications, such as pest control and crop protection.
Used in Dye and Pigment Production:
2-Chloro-4-methylbenzoic acid is also employed in the manufacturing process of dyes and pigments. Its chemical properties make it suitable for creating a wide range of colors and shades, which are used across various industries, including textiles, plastics, and printing inks.

InChI:InChI=1/C8H7ClO2/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)

Upstream product

• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 21423-84-7 2-chloro-4-methylbenzonitrile 
• 4395-80-6 2-chloro-1-isopropyl-4-methyl-benzene 
• 7697-37-2 nitric acid 
• 615-65-6 2-chloro-4-methyl-benzenamine 

Downstream Products

• 77769-89-2 4-methyl-2-p-toluidino-benzoic acid 
• 107412-82-8 2-phenoxy-4-methylbenzoic acid 
• 50-85-1 2-hydroxy-p-toluic acid 
• 144463-72-9 allyl 2-phenoxy-4-methylbenzoate 
• 99519-97-8 4-(4-chlorobenzoyl)-3-chlorotoluene 
• 99519-98-9 4-(4-chlorobenzoyl)-3-chlorobenzyl bromide 
• 99519-99-0 4-(4-chlorobenzoyl)-3-chlorobenzyl azide 
• 99519-83-2 5-amino-1-(4-[4-chlorobenzoyl]-3-chlorobenzyl)-1,2,3-triazole-4-carboxamide 
• 90649-68-6 1-(2-chloro-4-methylphenyl)ethan-1-one 
• 79913-56-7 3-chloro-2,6-dinitrotoluene 
• 876494-93-8 2-chloro-4-methyl-3,5-dinitro-aniline 
• 200265-74-3 2-chloro-4-methyl-3,5-dinitro-benzoyl chloride 
• 858004-06-5 2-chloro-4-methyl-3,5-dinitro-benzoyl azide 
• 25539-20-2 2-(phenoxy)terephthalic acid 

Relevant articles and documents

Benzohydroxamic acids as potent and selective anti-HCV agents

A diverse collection of 40 derivatives of benzohydroxamic acid (BHAs) of various structural groups were synthesized and tested against hepatitis C virus (HCV) in full-genome replicon assay. Some of these compounds demonstrated an exceptional activity, suppressing viral replication at sub-micromolar concentrations. The compounds were inactive against key viral enzymes NS3, and NS5B in vitro assays, suggesting host cell inhibition target(s). The testing results were consistent with metal coordination by the BHAs hydroxamic group in complex with a target(s). Remarkably, this class of compounds did not suppress poliomyelitis virus (PV) propagation in RD cells indicating a specific antiviral activity of BHAs against HCV.

INHIBITORS OF STEAROYL-COA DESATURASE

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.

Regiospecific chlorination of xylenes using K-10 montmorrillonite clay

Regiospecific chlorination of xylenes has been developed by employing NCS as a reagent and K-10 montmorrillonite clay as a solid support. Copyright Taylor & Francis Group, LLC.

Substituted alkylidene imidazoles

This disclosure relates to a class of novel substituted alkylidene imidazole derivatives and pharmaceutically acceptable salts thereof. The disclosure further describes pharmaceutical compositions containing such compounds and to the use of such compounds