7703-38-0

Basic information

• Product Name: Benzene, 1-nitro-4-[(phenylthio)methyl]-
• CAS NO: 7703-38-0
• Molecular Formula: C13H11NO2S
• Molecular Weight: 245.302
• Mol File: 7703-38-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Benzene, 1-nitro-4-[(phenylthio)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-nitro-4-[(phenylthio)methyl]-(7703-38-0)
• EPA Substance Registry System: Benzene, 1-nitro-4-[(phenylthio)methyl]-(7703-38-0)

Safety Data

• Hazardous Substances Data: 7703-38-0(Hazardous Substances Data)

Upstream product

• 3111-52-2 potassium thiophenolate 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 17530-84-6 4-nitrobenzyl phenyl sulfoxide 
• 591-50-4 iodobenzene 
• 100-68-5 methyl-phenyl-thioether 
• 42766-39-2 potassium 2-(4-nitrophenyl)acetate 
• 882-33-7 diphenyldisulfane 
• 26798-33-4 (p-nitrophenyl)methanethiol 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 619-73-8 4-nitrobenzyl chloride 
• 108-98-5 thiophenol 
• 99-99-0 1-methyl-4-nitrobenzene 
• 136497-64-8 4-aza-1-p-nitrobenzylazoniabicyclo<2.2.2>octane bromide 

Downstream Products

• 7693-38-1 α-Chloro-4-nitrobenzyl phenyl sulfone 
• 17530-84-6 4-nitrobenzyl phenyl sulfoxide 
• 34063-53-1 p-nitrobenzyl phenyl sulfone 
• 13738-70-0 (p-Aminobenzyl)-phenyl-sulfid 
• 13640-67-0 4-benzenesulfonylmethyl-aniline 
• 129527-31-7 1-(Benzenesulfonyl-bis-methylsulfanyl-methyl)-4-nitro-benzene 
• 736-30-1 1,2-bis(4-nitrophenyl)ethane 
• 882-33-7 diphenyldisulfane 
• 38042-51-2 α-Chlormethyl-(p-nitrophenyl)-phenylsulfoxid 
• 99-99-0 1-methyl-4-nitrobenzene 
• 139-66-2 diphenyl sulfide 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

Transition-metal-free decarboxylative thiolation of stable aliphatic carboxylates

A transition-metal-free decarboxylative thiolation protocol is reported in which primary, secondary, tertiary (hetero)aryl acetates and α-CN substituted acetates undergo the decarboxylative thiolation smoothly, to deliver a variety of functionalized aryl alkyl sulfides in moderate to excellent yields. Aryl diselenides are also amenable substrates for construction of C-Se bonds under the simple and mild reaction conditions. Moreover, the protocol is successfully applied to the late-stage modification of pharmaceutical carboxylates with satisfactory chemoselectivity and functional-group compatibility. This journal is

Alkyl Sulfides as Promising Sulfur Sources: Metal-Free Synthesis of Aryl Alkyl Sulfides and Dialkyl Sulfides by Transalkylation of Simple Sulfides with Alkyl Halides

A site-selective metal-free dealkylative approach to synthesize aryl alkyl and symmetrical dialkyl sulfides has been developed. This procedure is convenient and has wide functional group tolerance giving rise to sulfides carrying various alkyl chains from simple alkyl sulfides and alkyl halides in good to excellent yields. This transalkylation proceeds by an ionic mechanism via sulfonium intermediates and it was proposed that dimethylacetamide (DMAC) may participate in part to promote the reaction.

One-pot palladium-catalyzed borrowing hydrogen synthesis of thioethers

Palladium on magnesium oxide is able to allow a one-pot reaction to synthesize thioethers from thiols and aldehydes formed in situ from the respective alcohol by means of a borrowing hydrogen method. The reaction is initiated by dehydrogenation of the alcohol to give a palladium hydride intermediate and an aldehyde. The latter reacts with a thiol involving most probably the intermediacy of a thionium ion RCHi￡S+R, which can be reduced in situ by the metal hydride to afford thioethers. Lending support: Palladium nanoparticles on MgO catalyze the synthesis of thioethers from thiols and aldehydes formed in situ from alcohols by means of the borrowing hydrogen method (see scheme). Dehydrogenation of the alcohol gives a palladium hydride intermediate and an aldehyde. The latter reacts with a thiol through a thionium ion, which is reduced by the metal hydride to afford thioethers.