78269-85-9

Basic information

• Product Name: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&
• Synonyms: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&;N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide;Teoc-OSu;(TriMethylsilyl)ethoxycarbonyloxy]succiniMide;2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)-ethyl) carbonate;1-[[[2-(Trimethylsilyl)ethoxy]carbonyl]oxy]-2,5-pyrrolidinedione;Carbonic acid,2,5-dioxo-1-pyrrolidinyl [2-(triMethylsilyl)ethyl] ester;(triMethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione
• CAS NO: 78269-85-9
• Molecular Formula: C₁₀H₁₇NO₅Si
• Molecular Weight: 259.33
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
• Mol File: 78269-85-9.mol

Chemical Properties

• Melting Point: 83-88 °C(lit.)
• Boiling Point: 308.6°C at 760 mmHg
• Flash Point: 140.4°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.000675mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• CAS DataBase Reference: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&(78269-85-9)
• EPA Substance Registry System: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&(78269-85-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 78269-85-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Teoc-OSu is used as an acylating reagent for the synthesis of Teoc-amino acid derivatives, which are essential in the development of various pharmaceutical compounds. The reagent's ability to form stable derivatives with amino acids makes it a valuable tool in drug discovery and medicinal chemistry.
Used in Chemical Research:
In the field of chemical research, Teoc-OSu is utilized for the preparation of various organic compounds and materials. Its unique silicon-based structure allows for the exploration of new chemical reactions and the synthesis of novel molecules with potential applications in various industries.
Used in Material Science:
Teoc-OSu's silicon-based structure also makes it a candidate for use in material science, where it can be employed in the development of new materials with specific properties. These materials could have applications in electronics, coatings, or other advanced technologies.

InChI:InChI=1/C10H17NO5Si/c1-17(2,3)7-6-15-10(14)16-11-8(12)4-5-9(11)13/h4-7H2,1-3H3

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 20160-60-5 2-(trimethylsilyl)-ethoxycarbonyl chloride 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 74124-79-1 di(succinimido) carbonate 

Downstream Products

• 100821-66-7 Tmseoc-Phe-OH 
• 601494-35-3 1-(4-methoxybenzyl)-2-[3-(2-trimethylsilanylethoxycarbonylamino)phenyl]-1H-imidazole-4-carboxylic acid 4-methoxybenzyl ester 
• 863871-04-9 (2S,3S,4S,5R,6R)-3-Azido-4,5-bis-benzoyloxy-6-[2-oxo-4-(2-trimethylsilanyl-ethoxycarbonylamino)-2H-pyrimidin-1-yl]-tetrahydro-pyran-2-carboxylic acid 
• 887476-56-4 (S)-3-((1S,2R)-2-Benzyloxycarbonylamino-cyclopropyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid 
• 952685-54-0 tert-butyl (2S,3R)-4-(N-(4-cyanobenzylamino)-N-(2-trimethylsilylethoxycarbonyl)amino)-1-cyclohexyl-3-hydroxybutan-2-ylcarbamate 
• 952685-56-2 2-(trimethylsilyl)ethyl (2S,3S)-3-tert-butoxycarbonylamino-4-cyclohexyl-2-hydroxybutylcarbamate 
• 720721-32-4 (3R,4S)-4-[(benzyloxycarbonyl)amino]-3-[(tert-butoxycarbonyl)amino]piperidine-1-carboxylic acid 2-trimethylsilanylethyl ester 
• 887489-66-9 (S)-3-Methyl-2-{(S)-2-[(S)-5-nitro-2-(2-trimethylsilanyl-ethoxycarbonylamino)-pentanoylamino]-3-phenyl-propionylamino}-butyric acid methyl ester 
• 1027089-85-5 (S)-3-Methyl-2-{(S)-2-[(S)-6-nitro-2-(2-trimethylsilanyl-ethoxycarbonylamino)-hexanoylamino]-3-phenyl-propionylamino}-butyric acid methyl ester 
• 808102-87-6 [3-(3,5-dibromo-benzylamino)-propyl]-carbamic acid 2-trimethylsilanyl-ethyl ester 
• 808102-88-7 {3-[tert-butoxycarbonyl-(3,5-dibromo-benzyl)-amino]-propyl}-carbamic acid 2-trimethylsilanyl-ethyl ester 
• 200623-18-3 (2S,4S)-4-Amino-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-pyrrolidine-1-carboxylic acid 2-trimethylsilanyl-ethyl ester 
• 154876-20-7 1-hydrazinecarboxylic acid 2-(trimethylsilyl)ethyl ester 

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