79200-57-0 Usage
Description
(1R,2S,3R,4R)-2,3-DIHYDROXY-4-(HYDROXYMETHYL)-1-AMINOCYCLOPENTANE HYDROCHLORIDE is a complex organic compound with a cyclopentane ring structure, featuring four chiral centers and multiple hydroxyl and amino groups. (1R,2S,3R,4R)-2,3-DIHYDROXY-4-(HYDROXYMETHYL)-1-AMINOCYCLOPENTANE HYDROCHLORIDE is characterized by its unique stereochemistry and functional groups, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(1R,2S,3R,4R)-2,3-DIHYDROXY-4-(HYDROXYMETHYL)-1-AMINOCYCLOPENTANE HYDROCHLORIDE is used as a reagent in the synthesis of pyridofuran substituted pyrimidine derivatives, which are known as hepatitis C virus (HCV) replication (replicase) inhibitors. These inhibitors play a crucial role in the development of antiviral drugs targeting the replication process of HCV, offering a potential treatment for hepatitis C.
In the synthesis process, the compound serves as a key intermediate, providing the necessary structural elements and functional groups for the formation of the desired pyridofuran substituted pyrimidine derivatives. The chiral centers and hydroxyl groups in the compound contribute to the selectivity and specificity of the synthetic reactions, ensuring the production of the desired enantiomer with the correct stereochemistry.
Overall, (1R,2S,3R,4R)-2,3-DIHYDROXY-4-(HYDROXYMETHYL)-1-AMINOCYCLOPENTANE HYDROCHLORIDE is a valuable compound in the pharmaceutical industry, particularly for the development of antiviral agents against hepatitis C virus. Its unique structural features and potential applications highlight the importance of chiral chemistry and stereoselective synthesis in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 79200-57-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,2,0 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 79200-57:
(7*7)+(6*9)+(5*2)+(4*0)+(3*0)+(2*5)+(1*7)=130
130 % 10 = 0
So 79200-57-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO3/c7-4-1-3(2-8)5(9)6(4)10/h3-6,8-10H,1-2,7H2/p+1/t3-,4-,5-,6+/m1/s1
79200-57-0Relevant articles and documents
RNAs Containing Carbocyclic Ribonucleotides
Akabane-Nakata, Masaaki,Chickering, Tyler,Egli, Martin,Harp, Joel M.,Manoharan, Muthiah,Matsuda, Shigeo,Schlegel, Mark K.
supporting information, (2022/01/12)
Toward the goal of evaluation of carbocyclic ribonucleoside-containing oligonucleotide therapeutics, we developed convenient, scalable syntheses of all four carbocyclic ribonucleotide phosphoramidites and the uridine solid-support building block. Crystall
CARBOCYCLIC NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE
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Page 46-47, (2008/06/13)
The present invention provides carbocyclic nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such carbocyclic nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the carbocyclic nucleoside compounds of the present invention