800401-71-2

Basic information

• Product Name: 5-bromo-1H-pyrrolo[2,3-c] pyridine-2-carboxylic acid
• Synonyms: 5-bromo-1H-pyrrolo[2,3-c] pyridine-2-carboxylic acid;5-bromo-1H-pyrrolo[2,3-c];1H-Pyrrolo[2,3-C]pyridine-2-carboxylicacid, 5-broMo-
• CAS NO: 800401-71-2
• Molecular Formula: C8H5BrN2O2
• Molecular Weight: 241.044
• Product Categories: Heterocycle-Pyridine series
• Mol File: 800401-71-2.mol

Chemical Properties

• Boiling Point: 523.965 °C at 760 mmHg
• Flash Point: 270.684 °C
• Appearance: /
• Density: 1.947 g/cm³
• Refractive Index: 1.766
• Storage Temp.: 2-8°C
• PKA: 3.07±0.30(Predicted)
• CAS DataBase Reference: 5-bromo-1H-pyrrolo[2,3-c] pyridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1H-pyrrolo[2,3-c] pyridine-2-carboxylic acid(800401-71-2)
• EPA Substance Registry System: 5-bromo-1H-pyrrolo[2,3-c] pyridine-2-carboxylic acid(800401-71-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 800401-71-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid is used as a building block for the development of new drugs and pharmacologically active compounds due to its unique molecular structure and potential biological activities.
Used in Chemical Synthesis:
5-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid is used as a reactant in coupling reactions for the synthesis of complex organic compounds, leveraging its bromine atom and carboxylic acid group.
Used in Drug Development:
5-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid is used as a research compound to explore its potential applications in drug development, given its diverse biological activities and unique structure.
Used in Organic Synthesis Research:
5-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid is used as a subject of study in organic synthesis research to understand its reactivity, properties, and potential applications in creating new chemical entities.

InChI:InChI=1/C8H5BrN2O2/c9-7-2-4-1-5(8(12)13)11-6(4)3-10-7/h1-3,11H,(H,12,13)

Upstream product

• 800401-70-1 ethyl 5-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate 
• 21901-41-7 2-hydroxy-4-methyl-5-nitropyridine 
• 800401-69-8 ethyl 3-(2-bromo-5-nitro-4-pyridyl)-2-oxopropanoate 
• 23056-47-5 2-bromo-4-methyl-5-nitropyridine 
• 1215387-58-8 5-bromo-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS

Provided herein are compounds of Formula (I) and Formula (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.