80622-07-7

Basic information

• Product Name: N^ε-Cyclohexyloxycarbonyl-lysin
• Synonyms: N^ε-Cyclohexyloxycarbonyl-lysin
• CAS NO: 80622-07-7
• Molecular Weight: 272.345
• Mol File: 80622-07-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^ε-Cyclohexyloxycarbonyl-lysin(CAS DataBase Reference)
• NIST Chemistry Reference: N^ε-Cyclohexyloxycarbonyl-lysin(80622-07-7)
• EPA Substance Registry System: N^ε-Cyclohexyloxycarbonyl-lysin(80622-07-7)

Safety Data

• Hazardous Substances Data: 80622-07-7(Hazardous Substances Data)

Upstream product

• 13248-54-9 cyclohexyl chloroformate 
• 657-27-2 L-Lysine hydrochloride 

Downstream Products

• 89137-55-3 H-Thr-Pro-Lys(cHoc)-Ala-OBzl-Trifluoracetat 
• 89137-56-4 Boc-Tyr(Bzl)-Thr-Pro-Lys(cHoc)-Ala-OBzl 
• 89137-53-1 H-Pro-Lys(cHoc)-Ala-OBzl-Trifluoracetat 
• 89137-68-8 H-Thr-Pro-Lys(cHoc)-Ala-OBzl*Hydrochlorid 
• 89137-51-9 H-Lys(cHoc)-Ala-OBzl*Trifluoracetat 
• 89137-67-7 H-Pro-Lys(cHoc)-Ala-OBzl*Hydrochlorid 
• 89148-65-2 Boc-Thr-Pro-Lys(cHoc)-Ala-OBzl 
• 89148-64-1 Boc-Pro-Lys(cHoc)-Ala-OBzl 
• 89137-66-6 H-Lys(cHoc)-Ala-OBzl*Hydrochlorid 
• 80622-09-9 Boc-Lys(cHoc)-Ala-OBzl 
• 89137-58-6 H-Tyr(Bzl)-Thr-Pro-Lys(cHoc)-OBzl-Trifluoracetat 
• 80622-08-8 Boc-Lys(cHoc)-OH 

Relevant articles and documents

Cyclohexyloxycarbonyl based orthogonal solid phase peptide synthesis in Boc chemistry

Application of N-cyclohexyloxocarbonyl (Choc) protection in Boc chemistry on solid phase provides a new possibility for the preparation of protected peptide fragments. A Choc/OcHex protection scheme allows also the assembly of cyclic lactam peptides linked to the resin through the C- terminus. Choc protection is stable under the 1M TMSOTf-thioanisole/TFA cleavage condition at 0°C, but it is removable by anhydrous HF. We have utilized cyclohexyloxycarbonyl as an orthogonal protecting group for the synthesis of a i) bicyclic epitope peptide of glycoprotein D of HSV 1 on BHA resin and ii) fully protected hexapeptide involved in protein transport on Merrifield resin.