83079-77-0 Usage
General Description
(S) Alfa Aminobenzenebutanoic Acid 1,1-Dimethylethyl Ester, also known as t-Butyl 4-aminobutyric acid, is a chemical compound used in the pharmaceutical industry as an intermediate in the production of various drugs. (S) ALFA AMINOBENZENEBUTANOIC ACID 1,1-DIMETHYLETHYL ESTER is an ester derivative of t-Butyl 4-aminobutyric acid, which has an enlarged aliphatic side chain. It is commonly used as a neuroactive drug due to its ability to cross the blood-brain barrier and interact with the central nervous system. Additionally, it is also used in the synthesis of potential anti-epileptic and anti-convulsant medications. The compound may also have potential therapeutic applications in the treatment of anxiety, insomnia, and mood disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 83079-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,0,7 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 83079-77:
(7*8)+(6*3)+(5*0)+(4*7)+(3*9)+(2*7)+(1*7)=150
150 % 10 = 0
So 83079-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H21NO2.ClH/c1-14(2,3)17-13(16)12(15)10-9-11-7-5-4-6-8-11;/h4-8,12H,9-10,15H2,1-3H3;1H/t12-;/m0./s1
83079-77-0Relevant articles and documents
Asymmetric Synthesis of α-Amino Acids by Organocatalytic Biomimetic Transamination
Kang, Qi-Kai,Selvakumar, Sermadurai,Maruoka, Keiji
supporting information, p. 2294 - 2297 (2019/04/10)
A biomimetic enantioselective transamination of α-keto ester derivatives can be realized under mild conditions by using chiral quaternary ammonium arenecarboxylates in the absence of base additives. The corresponding α-amino acids can be used as versatile intermediates for further synthetic transformations that furnish chiral pyrrolidine and octahydroindolizine derivatives.
The effect of benzyl amine on the efficiency of the base-catalyzed transamination of α-keto esters
Xue, Fazhen,Xiao, Xiao,Wang, Haining,Shi, Yian
experimental part, p. 6862 - 6867 (2012/08/28)
This paper describes the effect of benzyl amine on the base-catalyzed transamination of α-keto esters. Among various benzyl amines examined, o-HOC6H4CH2NH2 was found to be highly effective for the reaction, affording a wide variety of α-amino esters in good yields. The o-OH group of the benzyl amine facilitates the transamination process likely via H-bond. Moderate enantiomeric excess was obtained for α-amino ester when a quinine derived catalyst was used.
