848072-60-6

Basic information

• Product Name: Oxiranemethanamine, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-
• CAS NO: 848072-60-6
• Molecular Formula: C20H22F3NO2
• Molecular Weight: 365.395
• Mol File: 848072-60-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxiranemethanamine, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanamine, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-(848072-60-6)
• EPA Substance Registry System: Oxiranemethanamine, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-(848072-60-6)

Safety Data

• Hazardous Substances Data: 848072-60-6(Hazardous Substances Data)

Upstream product

• 1092361-69-7 C₁₈H₁₇F₃NOS₂^(1-)*Na⁽¹⁺⁾ 
• 106-89-8 epichlorohydrin 
• 159216-80-5 N-benzyl-N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropyl-amine 
• 54910-89-3 FLUOXETINE 

Downstream Products

• 1092361-84-6 C₂₅H₃₁F₃N₂O₃S₂ 
• 1092361-86-8 azepine-1-carbodithioic acid 2-hydroxy-3-{methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-propyl ester 
• 1092361-87-9 benzyl-methyl-amino-1-carbodithioic acid 2-hydroxy-3-{methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-propyl ester 
• 1092361-83-5 pyrrolidine-1-carbodithioic acid 2-hydroxy-3-{methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-propyl ester 
• 1092361-85-7 C₂₆H₃₃F₃N₂O₂S₂ 
• 1092361-88-0 C₂₆H₃₄F₃N₃O₂S₂ 

Relevant articles and documents

Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides

Carbodithioic acid esters of fluoxetine have been prepared by replacing the methylamino function in aminopropane chain with carbodithioic acid ester group and by adding various S-2-hydroxypropyl ester of dialkyl carbodithioic acid at 3-methylamino group. Some of these compounds showed spermicidal, antifungal and anti-Trichomonas activities. The study revealed that incorporation of carbodithioic acid residue directly into fluoxetine structure leads to compounds with better antifungal and anti-Trichomonas activities, and N-methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]carbodithioic acid S-(2-pyrrolidino-ethyl) ester (14) has shown better profile than both fluoxetine and nonoxynol-9. Further lead optimization may yield a potent dual-function spermicide.