848488-03-9

Usage

Physical appearance

Pale yellow to amber liquid The compound has a light yellow to brownish color in its liquid state.

Odor

Floral, woody, and slightly fruity The compound has a complex aroma that combines floral, woody, and fruity scents.

Usage in fragrance and flavor industry

Synthetic musk fragrance ingredient It is commonly used as a component in creating artificial musk scents for various products.

Long-lasting scent

Often used in perfumes, soaps, and personal care products Due to its durability, the compound is a popular choice for incorporating into products that require a lasting fragrance.

Potential applications

Pharmaceuticals and research The unique chemical structure and properties of the compound make it a candidate for further exploration in drug development and scientific studies.

Safety precautions

Proper handling and storage required As with all chemicals, it is important to follow safety guidelines to minimize health and safety risks associated with the compound.

Upstream product

• 10601-19-1 5-methoxyindole-3-carboxaldehyde 
• 75-26-3 isopropyl bromide 
• 1006-94-6 5-methoxylindole 

Relevant academic research and scientific papers

Synthesis and Antiproliferative Activity of New N-Acylhydrazone Derivatives Containing Benzothiazole and Indole Based Moiety

Through a structure-based molecular hybridization strategy, a series of new N-acylhydrazone derivatives containing the benzothiazole and indole based moiety were designed, synthesized and screened for in vitro antiproliferative activity against Hep G2 cancer cell line. One compound (7a) exhibited excellent antiproliferative activity with IC50 values of 0.78 μM against Hep G2. In addition, C-5 substitutions of the indole ring of target compounds might be crucial for their cytotoxic activities. Additionally, the relative configuration of target compounds was confirmed as the E isomer. Further chemical manipulation of derivative 7a can make it possible to obtain new potential antitumor agents.

Reaction of 3/2-formylindoles with TOSMIC: Formation of indolyloxazoles and stable indolyl primary enamines

3-Formylindole and its 1-substituted and 1,5-disubstituted derivatives react with TOSMIC in presence of potassium carbonate in methanol under reflux to furnish 5-(3′-indolyl)oxazoles, new stable E-2-(3′-indolyl)-2- tosylethenamines and two diastereomers of N-[2-(3′-indolyl)-1,2-dimethoxy] ethylformamides. In contrast, 2-formylskatole furnishes N-(1-tosyl-2-skatolyl) ethenylformamide.