851513-47-8

Basic information

• Product Name: [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide
• Synonyms: [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide
• CAS NO: 851513-47-8
• Molecular Weight: 243.757
• Mol File: 851513-47-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide(851513-47-8)
• EPA Substance Registry System: [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide(851513-47-8)

Safety Data

• Hazardous Substances Data: 851513-47-8(Hazardous Substances Data)

Usage

General Description

[S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide is a chemical compound with the molecular formula C10H13ClNOS. It is a sulfinamide compound that contains a methyl group, a 4-chlorophenyl group, and a propanesulfinamide group. [S(S),N(E)]-2-methyl-N-[(4-chlorophenyl)methylene]-2-propanesulfinamide is commonly used as a reagent in chemical reactions and can be utilized in the synthesis of various organic compounds. It has potential applications in pharmaceutical and agrochemical industries as well. This chemical has a specific stereochemistry and is classified as an N-acyl-substituted thioamide, which makes it a valuable building block for the development of new compounds with potential biological and industrial applications.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 343338-28-3 (S)-2-methylpropane-2-sulfinamide 

Downstream Products

• 451503-28-9 (α¹R)-4-chloro-α-phenyl-benzenemethanamine hydrochloride 
• 451503-28-9 (α¹S)-4-chloro-α-phenyl-benzenemethanamine hydrochloride 
• 1174267-74-3 1-[(1,1-dimethylethyl)sulfinyl]-2-(4-chlorophenyl)aziridine 
• 1010692-93-9 dimethyl [(S_S,R)-(+)-(tert-butylsulfinylamino)(4-chlorophenyl)methyl]phosphonate 

Relevant articles and documents

Additive effects in the palladium-catalyzed carboiodination of chiral N-allyl carboxamides

The use of Pd catalysis as a means to synthesize organic halides has recently received increased attention. Among the reported methods is the Pd-catalyzed carboiodination, which uses extremely bulky ligands to facilitate carbon-halogen reductive eliminati

Synthesis of chiral aziridines through decarboxylative generation of sulfur ylides and their reaction with chiral sulfinyl imines

Reaction of sulfur ylides with a series of aryl substituted chiral nonracemic sulfinyl imines afforded the corresponding aziridines in good yields with good stereoselectivity. The sulfur ylides were generated by the thermally induced decarboxylation of carboxymethylsulfonium betaines. A drop in the diastereomeric ratio was observed when going from electron-deficient to electron-releasing aryl substituted imines. S-Methylene aziridinations involving the decarboxylation of carboxymethylsulfonium betaine functionality complements existing technologies with the advantages of the reaction protocol, levels of conversion, and scope.

KHSO4-mediated condensation reactions of tert-butanesulfinamide with aldehydes. Preparation of tert-butanesulfinyl aldimines

Optically pure tert-butanesulfinyl aldimines 1 were prepared by direct condensation of chiral tert-butanesulfinamide 3 with aldehydes 2 in high yields in the presence of KHSO4. The main advantage of KHSO4 is that it is applicable to the condensation reactions of a variety of aldehydes, including electron deficient and electron rich (hetereo)aromatic aldehydes, as well as aliphatic aldehydes.