860556-27-0 Usage
Uses
Used in Pharmaceutical Industry:
1-iodo-4-tert-pentyl-benzene is used as an intermediate in the synthesis of trans-Amorolfine (A634165), which is an analog and impurity of Amorolfine (A634170, HCl). Amorolfine is a morpholine antifungal drug and a topical solution used for the treatment of toenail infections. The use of 1-iodo-4-tert-pentyl-benzene in the synthesis process helps to improve the efficacy and safety of the final product, ensuring better treatment outcomes for patients suffering from fungal infections.
In addition to its role in the synthesis of Amorolfine, 1-iodo-4-tert-pentyl-benzene may also be utilized in the development of other pharmaceutical compounds. Its unique structure and properties make it a valuable building block for the creation of new drugs, potentially leading to breakthroughs in various medical fields. As research continues, the applications of 1-iodo-4-tert-pentyl-benzene may expand, further highlighting its importance in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 860556-27-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,5,5 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 860556-27:
(8*8)+(7*6)+(6*0)+(5*5)+(4*5)+(3*6)+(2*2)+(1*7)=180
180 % 10 = 0
So 860556-27-0 is a valid CAS Registry Number.
860556-27-0Relevant academic research and scientific papers
Clean preparation method of amorolfine hydrochloride intermediate
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Paragraph 0024-0029, (2019/12/09)
The invention discloses a clean preparation method of an amorolfine hydrochloride intermediate, and more specially relates to a preparation method of 4-iodo-tert-pentyl-benzene. According to the cleanpreparation method, a target product is prepared from t
Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine)
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Page/Page column 6, (2008/06/13)
The present invention discloses a new process for the preparation of 3-[4-(1,1-dimethyl-propyl)-phenyl]-2-methyl-propionaldehyde and for the preparation of cis-4-{3-[4-(1,1-dimethyl-propyl)-phenyl]-2-methyl-propyl}-2,6-dimethyl-morpholine (Amorolfine).