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FMOC-TRP-OPFP is a specialized chemical compound utilized in the field of peptide synthesis. It is composed of three distinct components: the FMOC group, which serves as a protective group for the amine group of an amino acid during synthesis; the TRP residue, representing tryptophan, an essential amino acid characterized by its large indole ring; and the OPFP group, another protective group for phenolic hydroxyl groups. FMOC-TRP-OPFP plays a crucial role in solid-phase peptide synthesis, ensuring the efficient and controlled synthesis of peptides by protecting the tryptophan residue.

86069-87-6

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86069-87-6 Usage

Uses

Used in Pharmaceutical Industry:
FMOC-TRP-OPFP is used as a protective agent for tryptophan residues during peptide synthesis for the development of pharmaceutical compounds. Its role in protecting the tryptophan side chain allows for the creation of complex peptide structures with greater precision and control, which is essential for the synthesis of therapeutic peptides and proteins.
Used in Research and Development:
In the research sector, FMOC-TRP-OPFP is employed as a key component in the synthesis of peptides for scientific studies. Its protective properties enable researchers to explore the properties and functions of peptides containing tryptophan, contributing to advancements in understanding protein structures and functions.
Used in Biochemistry and Molecular Biology:
FMOC-TRP-OPFP is utilized as a reagent in the synthesis of bioactive peptides and proteins for biochemical and molecular biological applications. Its ability to protect the tryptophan residue during synthesis is vital for the production of peptides with specific biological activities, facilitating research into protein-protein interactions, signal transduction pathways, and other molecular processes.
Overall, FMOC-TRP-OPFP is a versatile compound in the realm of peptide synthesis, playing a critical role in the development of pharmaceuticals, research studies, and understanding of biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 86069-87-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,0,6 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86069-87:
(7*8)+(6*6)+(5*0)+(4*6)+(3*9)+(2*8)+(1*7)=166
166 % 10 = 6
So 86069-87-6 is a valid CAS Registry Number.
InChI:InChI=1/C32H21F5N2O4/c33-25-26(34)28(36)30(29(37)27(25)35)43-31(40)24(13-16-14-38-23-12-6-5-7-17(16)23)39-32(41)42-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,38H,13,15H2,(H,39,41)/t24-/m0/s1

86069-87-6 Well-known Company Product Price

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  • Aldrich

  • (47479)  Fmoc-Trp-OPfp  ≥98.0%

  • 86069-87-6

  • 47479-5G

  • 2,523.69CNY

  • Detail

86069-87-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)propanoate

1.2 Other means of identification

Product number -
Other names Fmoc-L-tryptophan pentafluorophenyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86069-87-6 SDS

86069-87-6Relevant articles and documents

PREPARATION OF PENTAFLUOROPHENYL ESTERS OF FMOC PROTECTED AMINO ACIDS WITH PENTAFLUOROPHENYL TRIFLUOROACETATE

Green, Michael,Berman, Judd

, p. 5851 - 5852 (2007/10/02)

A high yield procedure for the preparation of pentafluorophenyl esters of Nα-9-fluorenylmethyloxycarbonyl protected amino acids is described.The procedure utilizes pentafluorophenyl trifluoroacetate.

9-Fluorenylmethyl Pentafluorophenyl Carbonate as a Useful Reagent for the Preparation of N-9-Fluorenylmethyloxycarbonylamino Acids and their Pentafluorophenyl Esters

Schoen, Istvan,Kisfaludy, Lajos

, p. 303 - 305 (2007/10/02)

9-Fluorenylmethyl pentafluorophenyl carbonate is a useful reagent for the efficient, side reaction-free introduction of N-9-fluorenylmethyloxycarbonyl protecting group into amino acids and for the subsequent preparation of their pentafluorophenyl esters.Some new compounds of both types are described.

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