86234-55-1

Basic information

• Product Name: ethyl 4-(ethylenediamine)benzoate
• Synonyms: ethyl 4-(ethylenediamine)benzoate
• CAS NO: 86234-55-1
• Molecular Weight: 208.26
• Mol File: 86234-55-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 4-(ethylenediamine)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(ethylenediamine)benzoate(86234-55-1)
• EPA Substance Registry System: ethyl 4-(ethylenediamine)benzoate(86234-55-1)

Safety Data

• Hazardous Substances Data: 86234-55-1(Hazardous Substances Data)

Upstream product

• 497-25-6 dimethylenecyclourethane 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 23239-88-5 benzocaine hydrochloride 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 107-15-3 ethylenediamine 

Relevant articles and documents

Development of an SNAr Reaction: A Practical and Scalable Strategy to Sequester and Remove HF

A simple and operationally practical method to sequester and remove fluoride generated through the SNAr reaction between amines and aryl fluorides is reported. Calcium propionate acts as an inexpensive and environmentally benign in situ scrubbe

The Use of 2-Oxazolidinones as Latent Aziridine Equivalents. 2. Aminoethylation of Aromatic Amines, Phenols, and Thiophenols

The utility of 2-oxazolidinones 1 as latent, carboxylated aziridine functionalities was examined.Reaction of 2-oxazolidinone (1a), 3-methyl2-oxazolidinone (1b), 3-(phenylmethyl)-2-oxazolidinone (1c), 3-phenyl-2-oxazolidinone (1d) 4,4-dimethyl-2-oxazolidinone (1e), and 5-ethyl-2-oxazolidinone (1f) with aromatic amine salts, phenol, or thiophenols at elevated temperatures (> 130 deg C) afforded aminoethylated adducts.The aminoethylation occurred with concomitant loss of carbon dioxide to furnish variously substituted N-aryl-1,2-ethanediamines 4, 1-(2-phenoxyethyl)-2-imidazolidinone (8), or 2-(arylthio)ethanamines 9 on reactions of 1 with aromatic amine salts, phenol, and thiophenols, respectively.Imidazolidinone 8 is believed to be a secondary reaction product resulting from the condensation of the initially formed 2-phenoxyethanamine with starting oxazolidinone 1a.The aminoethylation reaction did not proceed with aliphatic amine hydrochlorides or alkyl mercaptans.Preliminary mechanistic pathways for these ring openings were also investigated employing a specific, C-5 deuterium-labeled oxazolidinone 1b-d2.Ring-opening experiments of 1b-d2 with N-methylaniline hydrochloride suggest reaction can occur through either a dioxazolinium 5 and/or 5 intermediate.In contrast, reaction of 1b-d2 with thiophenol suggests ring-opening to proceed only via the dioxazolinium pathway.